SB-Ator 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Sunman birdem pharma ltd |
| Also available as |
Title
SB-Ator 10 mg Tablet
Categories
- Medicine
- Pharmaceuticals
- Cholesterol Lowering Drugs
- Statins
Description
SB-Ator 10 mg Tablet is a selective inhibitor of HMG-CoA reductase. It is used to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels. It is indicated to reduce total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia and for the treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia (Fredrickson Type IV).
Color options
- White
Dosage form
Tablet
Dosage strength
10 mg
Packaging
Blister pack
Pack size
30 tablets
Dimensions
- Length: 10cm
- Width: 5cm
- Height: 2cm
Active ingredient
Atorvastatin
Mechanism of action
Atorvastatin is a selective inhibitor of HMG-CoA reductase, responsible for the conversion of HMG-CoA to mevalonate, a precursor of sterols including cholesterol. It lowers plasma cholesterol and lipoprotein levels by inhibiting cholesterol synthesis in the liver and increasing the number of hepatic LDL receptors for enhanced uptake and catabolism of LDL.
Absorption
Rapidly absorbed after oral administration with maximum plasma concentrations occurring within 1 to 2 hours.
Bioavailability
Approximately 14%
Distribution
- Mean volume: 381 liters
- Plasma protein binding: 98%
Metabolism
- Pathways:
- Cytochrome P450 3A4 pathway
- Inhibition potential: In vitro studies suggest the importance of Atorvastatin metabolism by cytochrome P450 3A4, consistent with increased plasma concentrations of Atorvastatin in humans following coadministration with erythromycin.
Elimination
- Excretion: Primarily in bile
- Plasma elimination half life: Approximately 14 hours
Indication
- Heterozygous Familial Hypercholesterolaemia
- Homozygous Familial Hypercholesterolaemia
- Hypertriglyceridaemia
- Cardiac Ischaemic Events
- Hypercholesterolemia Associated with Diabetes Mellitus
Contraindications
- Hypersensitivity to any component of the medication
- Active liver disease
- Unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
Side effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Precautions
Liver function tests should be performed before initiation of treatment and periodically thereafter. Use with caution in patients who consume substantial quantities of alcohol or have a history of liver disease.
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical structure
- Molecular formula: C33H35FN2O5
- Image url: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg
Common questions
- What is SB-Ator 10 mg Tablet?
- How should I take SB-Ator 10 mg Tablet?
- What are the uses of SB-Ator 10 mg Tablet?
- What are the Side Effects of SB-Ator 10 mg Tablet?
- What are the instructions for storage and disposal SB-Ator 10 mg Tablet?
- Is SB-Ator 10 mg Tablet used for lowering cholesterol?
- Will taking SB-Ator 10 mg Tablet increase my risk of diabetes?
- For how long do I need to take SB-Ator 10 mg Tablet? Is it safe for long-term use?
- Does SB-Ator 10 mg Tablet cause weight loss?
- Can I stop taking SB-Ator 10 mg Tablet?
- Does SB-Ator 10 mg Tablet cause memory loss?
- Does SB-Ator 10 mg Tablet make you tired?
- Can SB-Ator 10 mg Tablet be prescribed to children?
- Is SB-Ator 10 mg Tablet a blood thinner?
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