Labeta 200 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Labetalol hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Hypertension in pregnancy
- Hypertensive crisis
- Anaesthesia for hypotensive technique
Pharmacology
- Adrenergic receptor-blocking agent
- Selective alpha 1-adrenergic action
- Nonselective beta-adrenergic action
- Decrease in blood pressure
- Peak plasma levels after oral administration
- Plasma half-life
- Urinary excretion
- Effect on renal function
Dosage & Administration
- Oral dosage for adults
- Oral dosage for severe hypertension
- Oral dosage for elderly patients
- Intravenous injection dosage
- Intravenous infusion dosage for different conditions
- Dosage for hypertensive anaesthesia
Interaction
- Enhancement of hypotensive effects by halothane
- Concomitant use with Class I antiarrhythmic agents
- Reduction in hypotensive effect when used with prostaglandin synthetase inhibitors
- Increase in incidence of tremor with tricyclic antidepressants
- Bioavailability modulation by cimetidine
Contraindications
- Hypersensitivity
- Heart block
- Heart failure
- Sick-sinus syndrome
- Cardiogenic shock
- Severe and prolonged hypotension or bradycardia
- Bronchial asthma or obstructive lung disorders
Side Effects
- Postural hypotension
- Tiredness
- Weakness
- Headache
- Rashes
- Scalp tingling
- Difficulty in micturition
- Epigastric pain
- Nausea
- Vomiting
- Liver damage
Pregnancy & Lactation
- Teratogenic studies in rats and rabbits
- Excretion in human milk
- Caution during nursing
Precautions & Warnings
- Severe hepatocellular injury
- Reversible hepatic injury
- Hepatic impairment considerations
- Peripheral vascular disease caution
Overdose Effects
- Excessive hypotension
- Excessive bradycardia
- Gastric lavage
- Pharmacologically induced emesis
- Atropine for bradycardia
- Digitalis glycoside for cardiac failure
- Vasopressors for hypotension
- Epinephrine for bronchospasm
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
Storage Conditions
- Cool & dry storage
- Protection from light
- Keep out of reach of children