Azinaaf 500 mg (Tablet)

Unit Price: ৳ 55.00 (4 x 3: ৳ 660.00)
Strip Price: ৳ 165.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Naafco pharma ltd
Also available as
Azinaaf 200 mg suspension

Title

  • Azinaaf 500 mg Tablet

Categories

  • Medicine
  • Antibiotic
  • Macrolide

Description

  • Azinaaf is indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, skin and soft tissue infections, and sexually transmitted diseases.
  • Azithromycin is acid-stable and can be taken orally with no need of protection from gastric acids. It is absorbed greater on an empty stomach.

Dosage

  • Adult dosage: 500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days. For sexually transmitted diseases caused by Chlamydia trachomatis in adults, the dose is 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days may also be given.
  • Children dosage: 10 mg/kg body weight once daily for 3 days for child over 6 months.

Mode of Action

  • Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and interfering with microbial protein synthesis.
  • Time to peak concentration in adults is 2.1 to 3.2 hours for oral dosage forms.

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Otitis media
  • Skin and soft tissue infections
  • Sexually transmitted diseases in men and women. Non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis.

Interaction

  • Antacid: Azithromycin should be taken at least 1 hour before or 2 hours after the antacid.
  • Cyclosporin: Caution should be exercised before co-administration with azithromycin.

Contraindications

  • Patients hypersensitive to Azithromycin or any other macrolide antibiotic.
  • Co-administration of ergot derivatives and Azithromycin.

Side Effects

  • Gastrointestinal side-effects such as nausea, abdominal discomfort, vomiting, flatulence, diarrhea, and loose stools.
  • Allergic reactions such as rash or photosensitivity.

Pregnancy & Lactation

  • Pregnancy Category B. Caution should be exercised when Azithromycin is administered to nursing women.

Precautions & Warnings

  • Rare serious allergic reactions, including angioneurotic oedema and anaphylaxis, have been reported.

Use in Special Populations

  • No dose adjustment is needed in patients with mild renal impairment.
  • Azithromycin should not be used in patients with hepatic disease.

Overdose Effects

  • Typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting, and diarrhea.

Storage Conditions

  • Keep in a dry place away from light and heat. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C38H72N2O12

Common Questions

  • Azinaaf 500 mg Tablet performs its action by preventing the synthesis of essential proteins required by bacteria.
  • Azinaaf 500 mg Tablet is used for the treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.

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