Azinaaf 200 mg/5 ml (Powder for Suspension)

20 ml bottle: ৳ 90.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Naafco pharma ltd
Also available as
Azinaaf 500 mg tablet

Title

  • Azinaaf 200 mg/5 ml Suspension

Categories

  • Antibiotic
  • Medication
  • Pharmacology

Description

  • Azinaaf is indicated for infections in lower respiratory tract, upper respiratory tract, otitis media, skin and soft tissue, and sexually transmitted diseases
  • Azithromycin is acid-stable and can therefore be taken orally
  • Azithromycin has high concentration in phagocytes and is actively transported to the site of infection
  • Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and interfering with microbial protein synthesis
  • Azithromycin's half-life allows a large single dose to be administered and yet maintain bacteriostatic levels in the infected tissue for several days

Dosage

  • The recommended adult oral dosage is 500 mg once daily for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days
  • For children, the dosage varies based on body weight and specific conditions
  • Azithromycin injection for IV infusion has specific recommended doses for different infections

Administration

  • Azithromycin should be taken at least 1 hour before or 2 hours after meals
  • Reconstitution procedure of suspension involves adding boiled and cooled water to the powdered form

Interaction

  • Azithromycin interaction with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, and terfenadine

Contraindications

  • Hypersensitivity to Azithromycin or any other macrolide antibiotic
  • Co-administration of ergot derivatives and Azithromycin
  • Patients with hepatic diseases

Side Effects

  • Mild to moderate gastrointestinal side-effects such as nausea, abdominal discomfort, vomiting, and diarrhea
  • Allergic reactions like rash or photosensitivity
  • Reversible elevations in liver transaminases
  • Rare cases of cholestatic jaundice and transient mild reductions in neutrofil counts
  • Reversible hearing impairment with prolonged usage

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during pregnancy and nursing as there are no adequate and well controlled studies in pregnant women

Precautions & Warnings

  • Rare serious allergic reactions reported, including angioneurotic oedema and anaphylaxis

Use in Special Populations

  • No dose adjustment needed in patients with mild renal impairment
  • Caution in using azithromycin in patients with severe renal impairment
  • Not to be used in patients with hepatic disease
  • No evidence of any effect on a patient's ability to drive or operate machinery

Overdose Effects

  • Typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting, and diarrhea
  • Gastric lavage and general supportive measures are indicated

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure available in an image form

FAQs

  • Commonly asked questions about Azinaaf 200 mg/5 ml Suspension

Related Brands