Betaloc 25 mg (Tablet)
Unit Price: ৳ 1.55 (7 x 14: ৳ 151.90)
Strip Price: ৳ 21.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Metoprolol tartrate |
| Company | Drug international ltd |
| Also available as |
Indications
- Management of hypertension
- Management of angina pectoris
- Treatment for cardiac arrhythmias
- Adjunct to the treatment of hyperthyroidism
- Reduction of infarct size in acute myocardial infarction
Pharmacology
- Selective beta1-blocker
- Reduction of heart rate
- Reduction of cardiac output
- Reduction of cardiac contractility
- Interference with insulin release
- Interference with carbohydrate metabolism
Dosage & Administration
- Total daily dosage of 100-400 mg for hypertension
- Single or twice-daily dosing
- Initial dose of 100 mg per day for hypertension
- Starting dose of 50 mg for angina pectoris
- Initial dose of 50 mg b.i.d for cardiac arrhythmias
- Recommendations for hyperthyroidism treatment
- Oral and IV dosing for myocardial infarction
- Individualized dosage for heart failure
Interaction
- Additive effect with catecholamine-depleting drugs
- Increased concentration with CYP2D6 inhibitors
- Risk of bradycardia with concomitant use of digitalis glycosides
- Exacerbation of rebound hypertension with clonidine withdrawal
Contraindications
- AV block
- Uncontrolled heart failure
- Severe bradycardia
- Sick-sinus syndrome
- Cardiogenic shock
- Severe peripheral arterial disease
- Known hypersensitivity to Metoprolol
Side Effects
- Tiredness
- Dizziness
- Depression
- Rash
- Shortness of breath
- Slow heart rate
- Headache
- Insomnia
- Nausea
- Dry mouth
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in breast milk
- Caution in nursing women
Precautions & Warnings
- Use with caution in patients with bronchospastic disease
- Controversy over withdrawing therapy prior to major surgery
- Masking of tachycardia during hypoglycemia
- Potential aggravation of arterial insufficiency with peripheral vascular disease
Use in Special Populations
- Caution in patients with impaired hepatic function
- Safety and effectiveness in pediatric patients
- Efficacy in geriatric patients
Overdose Effects
- Severe hypotension
- Sinus bradycardia
- Atrioventricular block
- Cardiac arrest
- Bronchospasm
- Impairment of consciousness
- Nausea
- Vomiting
Storage Conditions
- Cool and dry storage
- Protection from light