Zimax 500 mg (Tablet)

Unit Price: ৳ 40.00 (3 x 6: ৳ 720.00)

Strip Price: ৳ 240.00

Medicine Details

Category	Details
Generic	Azithromycin dihydrate
Company	Square pharmaceuticals plc
Also available as	Zimax 250 mg capsule Zimax 200 mg suspension Zimax 500 mg injection

Title

Zimax 500 mg Tablet

Description

Zimax 500 mg Tablet is indicated for a range of infections, including lower and upper respiratory tract infections, otitis media, skin and soft tissue infections, and sexually transmitted diseases. It acts by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

Indications

Lower respiratory tract infections
Upper respiratory tract infections
Otitis media
Skin and soft tissue infections
Sexually transmitted diseases

Pharmacology

Acid-stable
Readily absorbed
High concentration in phagocytes
Active transport to infection site
Bacteriostatic levels in infected tissue for several days
Half-life of 68 hours
Biliary excretion as major route of elimination

Dosage

Oral administration
Single dose for adults
Weight-based doses for children
Intravenous administration for specific infections

Administration

Reconstitution procedure of suspension:
- Shake the bottle well to loosen the powder
- Add boiled and cooled water up to the water mark of the bottle label
- Shake until powder is completely mixed with water
Timing of intake: Take at least 1 hour before or 2 hours after meal

Interaction

Antacid interaction
Carbamazepine interaction
Cyclosporin interaction
Digoxin interaction
Ergot derivatives interaction
Methylprednisolone interaction
Theophylline interaction
Warfarin interaction
Terfenadine interaction

Contraindications

Hypersensitivity to azithromycin or macrolide antibiotics
Co-administration with ergot derivatives
Hepatic diseases

Side effects

Mild to moderate gastrointestinal side-effects
Allergic reactions
Reversible elevations in liver transaminases
Rare cases of cholestatic jaundice
Transient mild reductions in neutrofil counts
Reversible hearing impairment in high-dose prolonged use

Pregnancy and lactation

Pregnancy Category B
No adequate and well-controlled studies in pregnant women
Caution during lactation

Precautions and warnings

Rare serious allergic reactions reported
Caution in renal impairment
Avoid in severe hepatic impairment
No effect on ability to drive or use machines

Overdose effects

Typical symptoms of macrolide antibiotic overdose
Supportive measures indicated

Storage conditions

Keep in a dry place away from light and heat
Keep out of the reach of children

Chemical structure

Molecular formula: C38H72N2O12
Chemical structure image: https://medex.com.bd/storage/res/g-res-100-azithromycin-dihydrate-chemical-structure-tFo4BQqfsRzQwcODCGo2.svg

Commonly asked questions

Zimax uses:
- Treatment and prevention of community-acquired pneumonia
- Treatment of pharyngitis/tonsillitis
- Treatment of skin and soft tissue infections
Side effects:
- Diarrhea
- Dry or scaly skin
- Abdominal pain
- Difficult or painful urination
- Vomiting
- Fever
- Acid or sour stomach
- Aggression or anger
- Excessive air or gas in the stomach
- Heartburn
Storage and disposal instructions: Keep in a cool dry place and its original packaging. Ensure it remains unreachable to children and pets.
Quick tips:
- Do not skip doses: Finish the full course of treatment even if feeling better
- Take with or after food: Take 1 hour before or 2 hours after food
- Antacid usage: Do not take antacids 2 hours before or after taking Zimax 500 mg Tablet
- Diarrhea side effect: Should stop when the course is complete, if not, consult a doctor
- Allergic reaction: Stop taking and inform the doctor if an itchy rash, swelling, or breathing difficulties occur