Betaone 50 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metoprolol tartrate |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Management of hypertension
- Management of angina pectoris
- Management of cardiac arrhythmias
- Adjunct in the treatment of hyperthyroidism
- Reduces infarct size in acute myocardial infarction
Pharmacology
- Selective beta1-blocker
- Reduces heart rate
- Reduces cardiac output
- Reduces cardiac contractility
- Reduces blood pressure
- Interferes with Insulin release
- Interferes with carbohydrate metabolism
- Interferes less with cardiovascular response to hypoglycaemia
Dosage & Administration
- Recommended dosage for hypertension
- Recommended dosage for angina pectoris
- Recommended dosage for cardiac arrhythmias
- Recommended dosage for hyperthyroidism
- Recommended dosage for acute myocardial infarction
- Usual initial dosage for extended-release tablet in hypertension
- Usual initial dosage for extended-release tablet in angina pectoris
- Usual initial dosage for extended-release tablet in heart failure
- Dosage for IV Injection in arrhythmias
- Dosage for IV Injection in surgery
- Dosage for IV Injection in myocardial infarction
Interaction
- Additive effect with catecholamine‐depleting drugs
- Increased concentration with CYP2D6 inhibitors
- Increased risk of bradycardia with digitalis glycosides
- Exacerbation of rebound hypertension with clonidine withdrawal
Contraindications
- AV block
- Uncontrolled heart failure
- Severe bradycardia
- Sick-sinus syndrome
- Cardiogenic shock
- Severe peripheral arterial disease
- Hypersensitivity to Metoprolol or other B-blockers
- Complicated myocardial infarction with bradycardia
- Complicated myocardial infarction with first-degree heart block
- Complicated myocardial infarction with systolic hypotension
- Complicated myocardial infarction with severe heart failure
Side Effects
- Tiredness
- Dizziness
- Depression
- Diarrhea
- Itching or rash
- Shortness of breath
- Slow heart rate
- Mental confusion
- Headache
- Somnolence
- Nightmares
- Insomnia
- Dyspnea
- Nausea
- Dry mouth
- Gastric pain
- Constipation
- Flatulence
- Digestive tract disorders
- Heartburn
- Pruritus
- Musculoskeletal pain
- Blurred vision
- Decreased libido
- Tinnitus
- Intensification of AV block
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in breast milk
- Caution during breastfeeding
Precautions & Warnings
- Use with caution in patients with bronchospastic disease
- Controversial withdrawal prior to major surgery
- Masking of tachycardia with hypoglycemia
- Precipitation or aggravation of symptoms in peripheral vascular disease
- Caution in concomitant use with calcium channel blockers
Use in Special Populations
- Use with caution in patients with impaired hepatic function
- No clinically relevant differences in pediatric patients
- Safety and effectiveness not established in patients <6 years of age
- No notable differences in efficacy or adverse events between older and younger patients
Overdose Effects
- Severe hypotension
- Sinus bradycardia
- Atrioventricular block
- Heart failure
- Cardiogenic shock
- Cardiac arrest
- Bronchospasm
- Impairment of consciousness
- Coma
- Nausea
- Vomiting
- Cyanosis
- Hypoglycemia
- Hyperkalemia
- Close monitoring of cardiovascular, respiratory, and renal function
- Close monitoring of blood glucose and electrolytes
- Treatment such as sympathomimetic agents, atropine, inotropic agents, and temporary pacing may be required
Storage Conditions
- Cool and dry place
- Protected from light