Albenda DS 400 mg (Chewable Tablet)

Unit Price: ৳ 3.40 (2 x 10: ৳ 68.00)
Strip Price: ৳ 34.00

Medicine Details

Category Details
Generic Albendazole
Company Aexim pharmaceuticals ltd

Title

  • Albenda DS

Categories

  • Medicine
  • Anthelmintic

Description

  • Benzimidazole anthelmintic
  • Vermicidal activity
  • Ovicidal activity
  • Larvicidal activity
  • Inhibitory effect on tubulin polymerization
  • Metabolized in the liver
  • Excreted in the urine

Indications

  • Hookworm infestation
  • Roundworm infestation
  • Threadworm infestation
  • Whipworm infestation
  • Strongyloides infestation
  • Tapeworm infestation
  • Opisthorchi infestation
  • Hydatid disease

Mode of Action

  • Blocks glucose uptake in helminths
  • Depletes energy level in helminths
  • Immobilizes parasites
  • Inhibits parasite tubulin polymerization
  • Extensively metabolized in the liver
  • Anthelmintic activity of metabolites
  • Excretion in urine

Dosage & Administration

  • 400 mg single dose for various infestations in adults and children over 2 years
  • 200 mg single dose for children of 1-2 years
  • Not recommended for children under 1 year
  • 400 mg twice daily for 28 days in hydatid disease for patients over 60 kg
  • 15 mg/kg body weight daily in hydatid disease for patients under 60 kg
  • 400 mg once daily for five days in giardiasis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Reduction of dose in children weighing less than 10 kg
  • Avoid in pregnancy and lactation
  • No dosage alteration needed in renal, hepatic or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders
  • Allergic shock
  • Convulsion
  • Meningism

Pregnancy & Lactation

  • FDA Pregnancy category C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment and during cycles
  • Breastfeeding
  • Constant medical supervision for echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in dry place
  • Away from light and heat
  • Keep out of the reach of children

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