Acubis 5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Concord pharmaceuticals ltd
Also available as
Acubis 25 mg tablet

Title

Acubis 5 mg Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmacology

Description

Beta-blocker medication used for hypertension, angina, and heart failure.

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • High affinity for ß1 receptor
  • Reduces heart rate and cardiac output
  • Low inter and intra-individual variability in plasma concentration profiles
  • High therapeutic reliability

Dosage & Administration

  • Adult: 5 mg once daily, may be increased to 10 mg and then to 20 mg if necessary
  • Children: Safety and effectiveness not established
  • Renal or Hepatic Impairment: Initial daily dose of 5 mg
  • Geriatrics: Dose adjustment usually not necessary

Interactions

  • Other β-blocking Agents: Should not be combined with other β-blocking agents
  • Catecholamine-Depleting Drugs: Patients receiving catecholamine-depleting drugs should be monitored closely
  • Centrally Active Antihypertensive Agents: May exacerbate rebound hypertension
  • Antiarrhythmic Agents: Use with care when myocardial depressants or inhibitors of A-V conduction are used concurrently
  • Calcium Channel Blockers: Combined use can lead to severe hypotension

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties

Pregnancy & Lactation

  • Pregnancy: Could be used if benefit justifies potential risk to the fetus
  • Lactation: Small amounts may be excreted in human milk

Precautions & Warnings

  • Impaired renal or hepatic function
  • Severe anaphylactic reaction history may result in heightened reactivity

Therapeutic Class

  • Beta blockers
  • Beta-adrenoceptor blocking drugs

Storage Conditions

Keep in a dry place away from light and heat, and out of the reach of children

Chemical Structure

  • Molecular Formula: C18H31NO4
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-135-bisoprolol-hemifumarate-chemical-structure-rpXCAgy2GIOFKWUs5Peu.svg

Common Questions

  • What is it used for: Lowering blood pressure, reducing heart workload, preventing chest pain
  • How to take it: By mouth, once daily, at the same time each day
  • Side Effects: Dizziness, Fatigue, Headache, Slow heart rate, Breathing difficulties, Cold extremities
  • Safety: Talk to doctor if have health conditions like asthma, diabetes, heart problems, liver or kidney problems, low blood pressure, depression
  • Storage and Disposal: Keep in cool dry place, in original packaging, and out of reach of children and pets
  • Quick Tips:
    • May cause dizziness
    • Can hide symptoms of low blood sugar
    • Do not stop suddenly

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