Bisten 2.5 mg (Tablet)

Unit Price: ৳ 5.00 (30's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Edruc limited
Also available as
Bisten 5 mg tablet Bisten 10 mg tablet

Title

  • Bisten 2.5 mg Tablet

Categories

  • Hypertension medication
  • Cardiovascular medication

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • Selective ß1 blocker
  • Reduces heart rate
  • Decreases arterial hypertension
  • Low inter and intra-individual variability of plasma concentration profiles
  • Metabolized via oxidative pathways
  • Renally eliminated metabolites
  • Primarily metabolized via CYPSA4
  • Elimination half-life of 10-12 hours

Dosage & Administration

  • Starting dose of 5 mg once daily
  • Dose may be increased to 10 mg or 20 mg once daily
  • Appropriate interval for dose titration is 2 weeks
  • Caution in patients with renal or hepatic impairment
  • No need to adjust dose in elderly unless significant renal or hepatic dysfunction

Interaction

  • Should not be combined with other β-blocking agents
  • Monitoring required with catecholamine-depleting drugs
  • Careful coadministration with centrally active antihypertensive agents and antiarrhythmic agents
  • Combined use with calcium channel blockers can lead to severe hypotension, bradycardia and cardiac failure

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut such as nausea, vomiting, diarrhea, constipation or abdominal pain
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to bronchospasm in asthma or COPD patients

Pregnancy & Lactation

  • Potential risk to the fetus, use during pregnancy only if benefit justifies the risk
  • Small amounts detected in the milk of lactating rats, unknown excretion in human milk

Precautions & Warnings

  • Use caution in adjusting the dose in patients with renal or hepatic impairment
  • Patients with history of severe anaphylactic reaction may be more reactive to allergens
  • Unresponsive to usual doses of epinephrine used to treat allergic reactions

Therapeutic Class

  • Anti adrenergic agent (Beta blockers)
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H31NO4
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-135-bisoprolol-hemifumarate-chemical-structure-rpXCAgy2GIOFKWUs5Peu.svg

Common Questions

  • What is Bisten 2.5 mg Tablet?
  • What is Bisten 2.5 mg Tablet used for?
  • How should I take Bisten 2.5 mg Tablet?
  • What are the side effects of Bisten 2.5 mg Tablet?
  • Is Bisten 2.5 mg Tablet safe to take?
  • Should I use Bisten 2.5 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Bisten 2.5 mg Tablet?

Quick Tips

  • May cause dizziness, rise slowly when getting up
  • Can hide symptoms of low blood sugar if diabetic, monitor levels regularly
  • Do not stop suddenly, can cause sudden blood pressure rise, increase risk of heart attack and stroke

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