Betafix 2.5 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
Category | Details |
---|---|
Generic | Bisoprolol hemifumarate |
Company | Healthcare pharmaceuticals ltd |
Also available as |
Product Title
- Betafix 2.5 mg Tablet
Categories
- Medicine
- Beta-blocker
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology
- Most selective ß1 blocker
- Reduces heart rate and cardiac output
- High therapeutic reliability
- Substantial absorption and bioavailability
- Metabolized via oxidative pathways
- Primarily metabolized via CYPSA4 and CYP2D6
- Elimination half-life of 10-12 hours
Dosage & Administration
- Usual starting dose is 5 mg once daily
- Dose individualized for mild to moderate hypertension
- Dose titration intervals of 2 weeks
- Increased dose beyond 20 mg once daily provides small incremental benefit
- Safety and effectiveness not established in children
Interaction
- Not to be combined with other β-blocking agents
- Close monitoring when combined with catecholamine-depleting drugs like reserpine
- Exacerbates rebound hypertension with concurrent use of clonidine
- Must be used with care when myocardial depressants or A-V conduction inhibitors are coadministered
- Combined use with calcium channel blockers can lead to severe hypotension, bradycardia, and cardiac failure
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Disturbances of the gut
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties due to bronchospasm
Pregnancy & Lactation
- Potential benefit justifying potential risk to fetus for use during pregnancy
- Mothers should stop nursing if considered essential
Precautions & Warnings
- Caution in adjusting dose for patients with renal or hepatic impairment
- Patients with severe anaphylactic reaction history may be more reactive to allergens when taking beta-blockers
Therapeutic Class
- Beta blockers
- Beta-adrenoceptor blocking drugs
- Anti adrenergic agent
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C<sub>18</sub>H<sub>31</sub>NO<sub>4</sub>
Commonly Asked Questions
- What is Betafix 2.5 mg Tablet?
- What is Betafix 2.5 mg Tablet used for?
- How should I take Betafix 2.5 mg Tablet?
- What are the side effects of Betafix 2.5 mg Tablet?
- Is Betafix 2.5 mg Tablet safe to take?
- Should I use Betafix 2.5 mg Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Betafix 2.5 mg Tablet?
- Quick Tips
Dimensions
- Not available
Color Options
- Not applicable
Functions
- Lowers blood pressure
- Reduces workload on the heart
- Prevents chest pain
Materials
- Bisoprolol Hemifumarate
Technical Specifications
- Single daily dose for therapeutic reliability
- Low inter and intra-individual variability of plasma concentration profiles
- Clearance balanced between renal elimination and hepatic metabolism
Design Elements
- Not available
Usability Features
- Usual starting dose is 5 mg once daily
- Dose titration intervals of 2 weeks
- Increased dose beyond 20 mg once daily provides small incremental benefit
Other Features
- Not available