Metocard 5 mg/5 ml (IV Injection)
5 ml ampoule: ৳ 120.40 (1 x 5: ৳ 602.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metoprolol tartrate |
| Company | Popular pharmaceuticals ltd |
Indications
- Management of hypertension and angina pectoris
- Treatment of cardiac arrhythmias
- Adjunct to hyperthyroidism treatment
- Reduces infarct size in acute myocardial infarction
- Pain relief and decrease in opiate analgesic need
- Reduces mortality in acute myocardial infarction patients
Pharmacology
- Selective beta1-blocker
- Reduces heart rate, cardiac output, and blood pressure
- Interferes less with insulin release and carbohydrate metabolism
- Interferes less with cardiovascular response to hypoglycemia
Dosage & Administration
- Different dosages for hypertension, angina, arrhythmias, hyperthyroidism, and myocardial infarction
- Variety of dosages for oral tablets and intravenous injections
- Gradual dose adjustments recommended for maintenance
- Individualized dosages for extended-release tablets
Interaction
- Additive effect with catecholamine-depleting drugs
- Increases Metocard concentration with CYP2D6 inhibitors
- Risk of bradycardia with digitalis glycosides and beta-blockers
- Exacerbation of rebound hypertension with clonidine withdrawal
Contraindications
- AV block, uncontrolled heart failure, severe bradycardia
- Sick-sinus syndrome, cardiogenic shock, severe peripheral arterial disease
- Known hypersensitivity to Metoprolol or other B-blockers
Side Effects
- Tiredness, dizziness, depression
- Diarrhea, itching, rash
- Shortness of breath, slow heart rate
- Headache, somnolence, insomnia
- Nausea, dry mouth, constipation
- Blurred vision, decreased libido, tinnitus
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in breast milk
- Caution in breastfeeding women
Precautions & Warnings
- Caution in bronchospastic diseases
- Considerations for major surgery
- Impact on diabetes, hypoglycemia, and peripheral vascular disease
- Caution with calcium channel blockers
- Use with caution in patients with impaired hepatic function
Use in Special Populations
- Use with caution in hepatic impaired patients
- Safety and effectiveness in pediatric patients
- No notable differences in geriatric use
Overdose Effects
- Manifestations include severe hypotension, bradycardia, heart failure
- Poisoning symptoms may include bronchospasm, impaired consciousness
- Treatment involves close monitoring and cardiovascular support
- Use of sympathomimetic agents, atropine, inotropic agents may be necessary