Diobis 2.5 mg (Tablet)
Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Title and Categories
- Diobis 2.5 mg Tablet
- Medicine
- Pharmaceuticals
- Beta-blocker
- Antihypertensive
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Mode of Action
- Selective ß1 blocker
- Decrease of arterial hypertension
- Reduction of heart rate and cardiac output
- Minimal impact on cholesterol fraction
- High absorption rate
- Extensive distribution
- Renal elimination of metabolites
Dosage and Administration
- Initial dose of 5 mg once daily
- Dose titration every 2 weeks
- Maximum dose of 20 mg once daily for hypertension
- Dosing adjustment for renal or hepatic impairment
- No established safety and effectiveness in children
- No need for dose adjustment in elderly unless with significant organ dysfunction
Interactions
- Avoid combination with other β-blocking agents
- Monitor closely when used with catecholamine-depleting drugs
- Careful coadministration with centrally active antihypertensive agents, antiarrhythmic agents, and calcium channel blockers
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Gastrointestinal disturbances
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm in asthma or COPD
Pregnancy & Lactation
- Potential teratogenic and fetotoxic effects in animal studies
- Use during pregnancy only if benefit justifies risk
- Limited excretion in human milk
- Consideration of essential use over nursing
Precautions & Warnings
- Caution in dose adjustment for impaired renal or hepatic function
- Increased reactivity to allergens in patients with history of severe anaphylactic reaction
- Unresponsiveness to usual doses of epinephrine in allergic reaction
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H31NO4
- Chemical Structure Image: [Link to Image]
Commonly Asked Questions
- What is Diobis 2.5 mg Tablet?
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- Is Diobis 2.5 mg Tablet safe to take?
- Should I use Diobis 2.5 mg Tablet empty stomach, before food or after food?
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- Quick Tips
Compound Summary
- Molecular Formula: C18H31NO4
- Chemical Structure Image: [Link to Image]