Tabis 2.5 mg (Tablet)

Unit Price: ৳ 6.02 (3 x 10: ৳ 180.60)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Navana pharmaceuticals ltd
Also available as
Tabis 5 mg tablet

Title

  • Tabis 2.5 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

  • Beta-blocker medication
  • Used for hypertension, angina, and heart failure
  • Blocks ß1 adrenergic receptor in the heart and vascular smooth muscle
  • Reduces heart rate and cardiac output resulting in decreased arterial hypertension
  • Can cause adverse effects on lipid metabolism
  • High therapeutic reliability based on pharmacokinetic properties
  • Bioavailability of 88%
  • Metabolized via oxidative pathways
  • Renally eliminated metabolites
  • Primarily metabolized via CYP3A4
  • Balanced clearance between renal elimination and hepatic metabolism
  • Elimination half-life of 10-12 hours
  • Adult and pediatric dosage guidelines
  • Dose adjustment in patients with renal or hepatic impairment
  • Precautions in patients with severe anaphylactic reaction history
  • Therapeutic class: Beta-blockers
  • Storage instructions

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Mode of Action

  • Selective ß1 blocker
  • Selective blockage of ß1 adrenergic receptor in the heart and vascular smooth muscle
  • Reduction in heart rate and cardiac output
  • Decrease in arterial hypertension
  • Adverse effects on lipid metabolism

Pharmacology

  • Affinity for ß1 receptor
  • Pharmacokinetic properties
  • Absorption and bioavailability
  • Distribution
  • Metabolism
  • Elimination

Dosage & Administration

  • Individualized for mild to moderate hypertension
  • Titration interval of 2 weeks
  • Dose increase based on response
  • Initial daily dose for patients with hepatic or renal impairment
  • Geriatric dose adjustment

Interaction

  • β-blocking Agents combination
  • Catecholamine-Depleting Drugs
  • Centrally Active Antihypertensive Agents
  • Antiarrhythmic Agents
  • Calcium Channel Blockers

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties
  • Bronchospasm

Pregnancy & Lactation

  • Teratogenic studies in rats
  • Fetotoxic and embryolethal effects
  • No studies in pregnant women
  • Excretion in human milk

Precautions & Warnings

  • Impaired renal or hepatic function caution
  • Severe anaphylactic reaction history

Therapeutic Class

  • Beta-blockers

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H31NO4

Common Questions

  • Usage instructions
  • Safety considerations
  • Side effects information
  • Dosage timing
  • Storage and disposal guidelines

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