Bisotab 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Pharmasia limited |
| Also available as |
Title
Bisotab 5 mg Tablet
Categories
- Antihypertensive
- Beta Blocker
- Heart Medication
- Pharmacology
- Medication Dosage
- Medical Interaction
- Contraindications
- Side Effects
- Pregnancy & Lactation
- Precautions & Warnings
- Therapeutic Class
- Storage Conditions
- Chemical Structure
- Common Questions
Description
Bisotab 5 mg Tablet is a beta-blocker medication used to treat hypertension, angina, and moderate to severe heart failure. It works by blocking adrenaline, lowering blood pressure, reducing the workload on the heart, and preventing chest pain. It has pharmacological properties that result in reduced heart rate and cardiac output. The medication is available in a 5 mg dosage for adults and should be used with caution in patients with renal or hepatic impairment. It has potential drug interactions with other beta-blocking agents, catecholamine-depleting drugs, centrally active antihypertensive agents, antiarrhythmic agents, and calcium channel blockers. It is contraindicated in patients with certain heart conditions such as cardiogenic shock, overt heart failure, and certain A-V blocks. Possible side effects may include fatigue, dizziness, headache, gastrointestinal disturbances, cold or numb extremities, muscle weakness or cramps, and breathing difficulties. Caution is advised for use during pregnancy and lactation. Storage should be in a dry place away from light and heat, and it should be kept out of the reach of children. The chemical structure reveals a molecular formula of C18H31NO4. Common questions about Bisotab 5 mg Tablet relate to its uses, side effects, safety, dosage administration, storage, and quick tips on precautions.
Attributes
- Indications:
- Hypertension
- Angina
- Moderate to severe heart failure
- Not recommended for emergency treatment of hypertensive crises
- Pharmacology:
- High affinity for ß1 receptor
- Reduces heart rate and cardiac output
- No adverse impact on cholesterol fraction
- High therapeutic reliability
- Excellent bioavailability
- Extensive distribution and metabolism
- Balanced renal elimination and hepatic metabolism
- Elimination half-life of 10-12 hours
- Dosage & Administration:
- Individualized treatment for mild to moderate hypertension
- Starting dose of 5 mg once daily
- Dose titration at an appropriate interval of 2 weeks
- Limited data for use in children
- Caution in patients with renal or hepatic impairment
- No adjustment usually necessary for geriatric patients
- Interaction:
- Not recommended with other beta-blocking agents
- Monitor closely when combined with catecholamine-depleting drugs
- May exacerbate rebound hypertension when used with centrally active antihypertensive agents such as clonidine
- Should be used with care when concurrently administered with certain calcium channel blockers
- Contraindications:
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure due to pulmonary hypertension
- Sinus bradycardia
- Side Effects:
- Fatigue
- Dizziness
- Headache
- Gastrointestinal disturbances
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties (bronchospasm in patients with asthma or COPD)
- Pregnancy & Lactation:
- Not teratogenic in rats at normal doses
- Fetotoxic and embryolethal at high doses
- No studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Small amounts detected in the milk of lactating rats
- Caution advised if essential to use in lactating women
- Precautions & Warnings:
- Caution in adjusting dose for patients with renal or hepatic impairment
- Patients with a history of severe anaphylactic reaction may be more reactive to allergens and unresponsive to usual doses of epinephrine
- Therapeutic Class:
- Anti adrenergic agent (Beta blockers)
- Beta-adrenoceptor blocking drugs
- Beta-blockers
- Storage Conditions:
- Keep in dry place away from light and heat
- Keep out of the reach of children
- Chemical Structure:
- Molecular Formula: C18H31NO4
- Common Questions:
- Uses of Bisotab 5 mg Tablet
- Recommended dosage administration
- Possible side effects and safety concerns
- Administration with or without food
- Storage and disposal instructions
- Quick tips for dizziness and low blood sugar monitoring