C-2 500 mg (Tablet)
Unit Price: ৳ 45.13 (1 x 8: ৳ 361.00)
Strip Price: ৳ 361.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Astra biopharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
- Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
- Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains)
- Skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains)
- Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Well-characterized and effective antibacterial agent
- Broad-spectrum bactericidal activity against a wide range of common pathogens
- Good stability to bacterial beta-lactamase
- Active against many ampicillin-resistant and amoxycillin-resistant strains
Dosage
- Dosage for adolescents and adults (13 years and older)
- Dosage for pediatric patients (3 months to 12 years)
- Dosage for parenteral administration
- Dosage for specific conditions like pneumonia, acute exacerbations of chronic bronchitis, gonorrhoea, meningitis, bone and joint infections
- Specific dosages for different types of infections
Administration
- Use of freshly reconstituted solution recommended
- Potency maintenance for at least 24 hours at room temperature or 48 hours at 5°C
Interaction
- No potentially hazardous interactions reported
Contraindications
- Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects occurred infrequently
- Effects reported include rashes and gastrointestinal disturbances
- Prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida
Pregnancy & Lactation
- US FDA pregnancy category of Cefuroxime is B
- No adequate and well-controlled studies in pregnant women
- Excreted in human milk
- Caution advised when administered to a nursing woman
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis
- Cephalosporin antibiotics in general may be given safely to patients who are hypersensitive to penicillin although cross reactions have been reported
- Likely safe at recommended dose levels
Therapeutic Class
- Second generation Cephalosporins
Reconstitution
- Specific instructions for reconstituting intramuscular and intravenous injections
Storage Conditions
- Cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of the reach of children