Gimrox 125 mg/5 ml (Powder for Suspension)

70 ml bottle: ৳ 190.00

Medicine Details

Category Details
Generic Cefuroxime axetil
Company Globex pharmaceuticals ltd
Also available as
Gimrox 250 mg tablet Gimrox 500 mg tablet Gimrox 750 mg injection

Title

Gimrox

Categories

  • Antibiotics
  • Medication
  • Pharmaceuticals

Description

Gimrox is a second generation Cephalosporin antibiotic indicated for the treatment of various bacterial infections.

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections including pneumonia
  • Skin and skin-structure infections
  • Urinary tract infections
  • Bone and Joint Infections
  • Gonorrhea
  • Early Lyme Disease (erythema migrans)

Pharmacology

Cefuroxime is a broad-spectrum bactericidal antibiotic with good stability to bacterial β-lactamase.

Dosage

  • TabletOrSuspension:
    • AdolescentsAndAdults:
      • PharyngitisTonsillitis: 250 mg b.i.d. for 5-10 days
      • AcuteBacterialMaxillarySinusitis: 250 mg b.i.d. for 10 days
      • AcuteBacterialExacerbationOfChronicBronchitis: 250-500 mg b.i.d. for 10 days
      • UncomplicatedSkinInfections: 250-500 mg b.i.d. for 10 days
      • UncomplicatedUrinaryTractInfections: 250 mg b.i.d. for 7-10 days
    • PaediatricPatients:
      • PharyngitisTonsillitis: 20 mg/kg/day b.i.d for 5-10 days
      • AcuteOtitisMedia: 30 mg/kg/day b.i.d for 10 days
      • AcuteBacterialMaxillarySinusitis: 30 mg/kg/day b.i.d for 10 days
  • Parenteral:
    • Adult: 750 mg three times daily by IM or IV injection
    • Children: 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
    • Neonate: 30 - 100 mg/kg/day given in 2 or 3 equally divided doses

Administration

Freshly reconstituted solution is recommended; maintains potency for at least 24 hours at room temperature or 48 hours at 5°C.

Interaction

No potentially hazardous interactions reported.

Contraindications

Contraindicated in patients with known allergy to Cephalosporins.

SideEffects

  • Rashes
  • Gastrointestinal disturbances
  • Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.

PregnancyAndLactation

  • PregnancyCategory: B
  • Notes: Use during pregnancy only if clearly needed; caution should be exercised when administered to a nursing woman.

PrecautionsAndWarnings

Use with care in patients receiving concurrent treatment with potent diuretics & those with a history of colitis; cross reactions with penicillin hypersensitivity have been reported.

TherapeuticClass

Second generation Cephalosporins

Reconstitution

Specific reconstitution instructions provided for intramuscular and intravenous injections.

StorageConditions

Store below 30°C, away from light & moisture; keep out of the reach of children.

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