Topress 50 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metoprolol tartrate |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Management of hypertension
- Management of angina pectoris
- Treatment of cardiac arrhythmias
- Adjunct in the treatment of hyperthyroidism
- Reduction of infarct size in acute myocardial infarction
- Pain relief
Pharmacology
- Selective beta1-blocker
- Reduction of heart rate
- Reduction of cardiac output
- Reduction of cardiac contractility
- Interference with insulin release
- Interference with carbohydrate metabolism
Dosage & Administration
- Total daily dosage range of 100-400 mg
- Single or twice-daily dosing
- Different dosages for hypertension, angina, arrhythmias, hyperthyroidism, and myocardial infarction
- Extended-release tablet options
- Dosage adjustments for heart failure
- Intravenous injection dosages for arrhythmias and myocardial infarction
Interaction
- Additive effect with catecholamine-depleting drugs
- Potential increase in concentration with CYP2D6 inhibitors
- Increase in risk when used with digitalis glycosides
- Exacerbation of rebound hypertension with clonidine withdrawal
Contraindications
- AV block
- Uncontrolled heart failure
- Severe bradycardia
- Sick-sinus syndrome
- Cardiogenic shock
- Severe peripheral arterial disease
Side Effects
- Tiredness
- Dizziness
- Depression
- Diarrhea
- Rash
- Shortness of breath
- Slow heart rate
- Mental confusion
- Headache
- Insomnia
- Nausea
- Dry mouth
- Blurred vision
- Decreased libido
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in breast milk
- Caution during lactation
Precautions & Warnings
- Caution in bronchospastic diseases
- Considerations for major surgery
- Impact on diabetes and hypoglycemia
- Effects on peripheral vascular disease
Use in Special Populations
- Caution in hepatic impaired patients
- Safety and effectiveness in pediatric use
- No notable differences in geriatric use
Overdose Effects
- Severe hypotension
- Sinus bradycardia
- Atrioventricular block
- Cardiac arrest
- Bronchospasm
- Impairment of consciousness
- Nausea
- Vomiting
- Cyanosis
Storage Conditions
- Cool and dry place
- Protected from light