Rofurox 250 mg (Tablet)
Unit Price: ৳ 40.00 (1 x 10: ৳ 400.00)
Strip Price: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae
- Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Broad-spectrum bactericidal activity against a wide range of common pathogens
- Good stability to bacterial β-lactamase
- Active against many ampicillin-resistant and amoxycillin-resistant strains
Dosage
- Dosage for Adolescents and adults
- Dosage for Paediatric Patients
- Parenteral Dosage for Adults
- Dosage for Children above 3 months of age
- Dosage for Neonate
- Dosage for Meningitis
- Dosage for bone and joint infections
- Dosage for Community acquired pneumonia
- Dosage for MDR Typhoid Fever
- Dosage for Early Lyme disease
- Dosage for Impetigo
Administration
Use of freshly reconstituted solution is recommended
Interaction
No potentially hazardous interactions reported
Contraindications
Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects occurred infrequently
- Effects reported include rashes and gastrointestinal disturbances
- Prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida
Pregnancy & Lactation
- US FDA pregnancy category of Cefuroxime is B
- No adequate and well-controlled studies in pregnant women
- Cefuroxime excreted in human milk
- Caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis
- Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin
- Cross reactions have been reported
- Unlikely problem at the recommended dosage levels
Therapeutic Class
Second generation Cephalosporins
Reconstitution
- For 750 mg intramuscular injection: Add water for injection to vial and then shake gently for dispersion
- For 750 mg intravenous injection: Add water for injection to vial and then shake gently for dispersion
- For 1.5 g intravenous injection: Add water for injection to vial and then shake gently for dispersion
Storage Conditions
Store in a cool, dry place (below 30<sup>o</sup> C), away from light & moisture. Keep out of the reach of children