Amfrad 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 80.24
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Amulet pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Susceptible microorganisms
- Gram-positive bacteria
- Gram-negative bacteria
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in bacteria
- Cell wall action
Dosage & Administration
- Oral administration for adults and children
- Injectable administration for adults and children
- Dose variations based on infection severity
Interaction
- Risk of kidney damage with nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Glossitis
- Dizziness
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Vaginitis
- Candida overgrowth
- Blood disorders
- Fever
- Joint pains
- Oedema
Pregnancy & Lactation
- Potential teratogenicity
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Risk of superinfection with prolonged use
- Care in patients hypersensitive to penicillins
- Potential positive result in Coombs' testing
- Possible false positive urine glucose result
Use in Special Populations
- Recommended doses for renal impairment and haemodialysis
- Higher doses for chronic or severe infections
- Continued treatment for certain infections
Overdose Effects
- Non-specific symptoms
- Nausea
- Vomiting
- Diarrhoea
- Gastric upsets
- Supportive treatment
- Gastric lavage if necessary
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Limited shelf life for reconstituted suspension
- Usage duration for injection solutions
- Colour variation in reconstituted solutions
- Expiry date adherence
- Keep out of reach of children
- Dispensed on prescription