Amfrad 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.24

Medicine Details

Category Details
Generic Cephradine
Company Amulet pharmaceuticals ltd
Also available as
Amfrad 500 mg capsule Amfrad 250 mg capsule

Indications

  • Treatment of infections caused by sensitive bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms
  • Gram-positive bacteria
  • Gram-negative bacteria

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria
  • Cell wall action

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dose variations based on infection severity

Interaction

  • Risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Vaginitis
  • Candida overgrowth
  • Blood disorders
  • Fever
  • Joint pains
  • Oedema

Pregnancy & Lactation

  • Potential teratogenicity
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Care in patients hypersensitive to penicillins
  • Potential positive result in Coombs' testing
  • Possible false positive urine glucose result

Use in Special Populations

  • Recommended doses for renal impairment and haemodialysis
  • Higher doses for chronic or severe infections
  • Continued treatment for certain infections

Overdose Effects

  • Non-specific symptoms
  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets
  • Supportive treatment
  • Gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Limited shelf life for reconstituted suspension
  • Usage duration for injection solutions
  • Colour variation in reconstituted solutions
  • Expiry date adherence
  • Keep out of reach of children
  • Dispensed on prescription

Related Brands