Alphapress 2 mg (Tablet)
Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prazosin hydrochloride |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of Hypertension
- Treatment of Left Ventricular Failure
- Treatment of Raynaud's Phenomenon and Disease
- Symptomatic treatment of Benign Prostatic Hyperplasia
Pharmacology
- Decrease in total peripheral vascular resistance
- Selective inhibition of postsynaptic alpha-1-adrenoreceptors
- Effect on blood pressure in hypertensive patients
- Effect on left ventricular filling pressure and cardiac output
- Reduction in severity of signs and symptoms of Raynaud's disease
- Improvement in urinary pressure profile in men with BPH
- No adverse changes in serum lipid profile
Dosage & Administration
- Initial therapy with a low starting dose
- Dosage adjustment based on patient's response
- Use as initial and sole agent or in combination with other antihypertensive drugs
- Various dosage regimens for hypertension
- Recommended starting dosage for Left Ventricular Failure, Raynaud's, and BPH
- Prazosin XR Extended-Release Tablets dosage initiation and titration
Interaction
- No adverse drug interaction observed in clinical experience
- Details of no adverse interaction with specific drug categories
Contraindications
- Contraindicated in patients with known sensitivity to quinazolines
Side Effects
- Common reactions including dizziness, headache, drowsiness, palpitations, nausea
- Other reactions such as vomiting, diarrhea, edema, orthostatic hypotension, rash, impotence
- Occasional reports of worsening of pre-existing narcolepsy
- Specific side effects in patients with left ventricular failure and Raynaud's Phenomenon/Disease
Pregnancy & Lactation
- No teratogenic effects seen in animal testing
- Use during pregnancy and lactation should be cautious and justified by potential benefit
Precautions & Warnings
- Caution for postural hypotension in hypertension
- Importance of observance of recommended starting dose in Left Ventricular Failure
- Monitoring of blood pressure and medication interactions in Raynaud's and BPH
Use in Special Populations
- Not recommended for children under 12 years
- Not recommended in specific conditions of left ventricular failure
- No adequate data for efficacy in recent myocardial infarction
Overdose Effects
- Management of accidental ingestion overdose effects
- Support of the cardiovascular system in case of hypotension
- Monitoring and support of renal function
Therapeutic Class
- Alpha adrenoceptor blocking drugs
Storage Conditions
- Store below 30°C, away from light and moisture
- Keep out of reach of children