Prazopress 1 mg (Tablet)

Unit Price: ৳ 4.00 (3 x 10: ৳ 120.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Unimed unihealth pharmaceuticals ltd
Also available as
Prazopress 2 mg tablet Prazopress er 25 mg tablet Prazopress er 5 mg tablet

Indications

  • Hypertension
  • Left Ventricular Failure
  • Raynaud's Phenomenon And Raynaud's Disease
  • Benign Prostatic Hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of postsynaptic alpha-1-adrenoreceptors
  • Therapeutic efficacy in patients with congestive heart failure
  • Reduction in left ventricular filling pressure
  • Reduction in cardiac impedance
  • Augmentation of cardiac output
  • Improvement of urinary pressure profile in men with benign prostatic hyperplasia
  • No adverse changes in the serum lipid profile

Dosage & Administration

  • Therapy initiated with a low starting dose
  • Dosage adjusted according to the patient's individual toleration
  • Small increases in dosage until the desired effect is achieved
  • Recommended starting dose for left ventricular failure: 0.5 mg two, three or four times a day
  • Recommended starting dosage for Raynaud's Phenomenon And Raynaud's Disease: 0.5 mg b.i.d.
  • Recommended starting dose for Benign Prostatic Hyperplasia: 0.5 mg twice daily

Interaction

  • No adverse drug interaction with cardiac glycosides, hypoglycemic agents, tranquilizers, sedatives, antiarrhythmic agents, and analgesic, antipyretic, and anti-inflammatory agents

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Lack of energy
  • Weakness
  • Palpitations
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal discomfort
  • Liver function abnormalities
  • Pancreatitis
  • Edema
  • Orthostatic hypotension
  • Dyspnea
  • Faintness
  • Tachycardia
  • Nervousness
  • Vertigo
  • Hallucinations
  • Depression
  • Rash
  • Pruritus
  • Alopecia
  • Urinary frequency
  • Impotence
  • Incontinence
  • Priapism
  • Blurred vision
  • Reddened solera
  • Epistaxis
  • Tinnitus
  • Dry mouth
  • Nasal congestion
  • Diaphoresis
  • Fever
  • Positive ANA liter
  • Arthralgia
  • Worsening of pre-existing narcolepsy

Pregnancy & Lactation

  • Use during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus
  • Excreted in small amounts in human milk

Precautions & Warnings

  • Occasional exaggerated response leading to postural hypotension
  • Observance of the recommended starting dose in left ventricular failure
  • Careful monitoring of blood pressure during administration for Raynaud's and benign prostatic hyperplasia

Use in Special Populations

  • Not recommended for children under the age of 12 years
  • Not recommended for left ventricular failure due to mechanical obstruction

Overdose Effects

  • Support of the cardiovascular system is of first importance
  • Renal function monitored and supported as needed
  • Prazosin is not dialyzable because it is protein bound

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Keep away from light and moisture
  • Store below 30°C
  • Keep away from reach out of the children

Related Brands