Elocef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Ethical drugs limited |
| Also available as |
Title
- Elocef
Categories
- Antibiotics
- Medication
- Pharmaceutical
Description
- Elocef is a broad-spectrum bactericidal antibiotic
- It is active against infections caused by both gram-positive and gram-negative microorganisms
- It is indicated for the treatment of upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections
- It is excreted in breast milk and should be used with caution in lactating mothers
- Dosage adjustment is necessary in renal impairment
Color Options
- White
Functions
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Inhibition of cross-linking process in bacteria cell wall resulting in lysis of bacteria
- Prevention of rheumatic fever or glomerulonephritis resulting from infections with haemolytic streptococci
Materials
- Cephradine
- Peptidoglycan
Technical Specifications
- Broad spectrum antibiotic
- Cell wall inhibitor
- Bactericidal
- Active against penicillinase producing and nonproducing staphylococci
Design Elements
- First generation Cephalosporin
Usability Features
- Oral and injectable administration
Indications
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections
- Treatment of skin and soft tissue infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Main site of action is the cell wall of bacteria
Dosage & Administration
- Varied dosage for adults based on the type and severity of infection
- Varied dosage for children based on the type and severity of infection
- Usual dose for adults in injectable administration
- Dose for children in injectable administration
- Dosage adjustment necessary in elderly, renal or hepatic impairment
Interaction
- Increased risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced possibility of renal toxicity with diuretics and probenecid
Contraindications
- Not to be used in patients with known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Possible occurrence of skin reactions, glossitis, heartburn, dizziness, tightness in the chest, nausea, vomiting, diarrhea, abdominal pain, vaginitis, candida overgrowth
- Rare blood and lymphatic system disorders
- Rare immune system disorders
- Rare psychiatric disorders
- Rare nervous system disorders
- Rare hepatobiliary disorders
- Rare renal and urinary disorders
- Unknown investigation results
Pregnancy & Lactation
- Safety in pregnancy not established
- Excreted in breast milk
- Caution advised for lactating mothers
Precautions & Warnings
- Prolonged use may result in superinfection
- Administered with care to patients hypersensitive to penicillins
- May cause false positive urine glucose result with certain tests
- Lactose content
- Dosage adjustment necessary in renal impairment
Use in Special Populations
- Dosing recommendations for patients with renal impairment
- Additional information for all patients
- Restriction on pediatric dosages
Overdose Effects
- Non-specific symptoms
- Need for supportive treatment
- Possibility of gastric lavage if large amount ingested
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Limited shelf life of reconstituted suspension
- Limited shelf life of injection solutions
- Color variation in reconstituted solutions
- Do not use later than the date of expiry
- Keep out of reach of children