Elocef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Ethical drugs limited
Also available as
Elocef 250 mg capsule Elocef 500 mg capsule

Title

  • Elocef

Categories

  • Antibiotics
  • Medication
  • Pharmaceutical

Description

  • Elocef is a broad-spectrum bactericidal antibiotic
  • It is active against infections caused by both gram-positive and gram-negative microorganisms
  • It is indicated for the treatment of upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections
  • It is excreted in breast milk and should be used with caution in lactating mothers
  • Dosage adjustment is necessary in renal impairment

Color Options

  • White

Functions

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Inhibition of cross-linking process in bacteria cell wall resulting in lysis of bacteria
  • Prevention of rheumatic fever or glomerulonephritis resulting from infections with haemolytic streptococci

Materials

  • Cephradine
  • Peptidoglycan

Technical Specifications

  • Broad spectrum antibiotic
  • Cell wall inhibitor
  • Bactericidal
  • Active against penicillinase producing and nonproducing staphylococci

Design Elements

  • First generation Cephalosporin

Usability Features

  • Oral and injectable administration

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Main site of action is the cell wall of bacteria

Dosage & Administration

  • Varied dosage for adults based on the type and severity of infection
  • Varied dosage for children based on the type and severity of infection
  • Usual dose for adults in injectable administration
  • Dose for children in injectable administration
  • Dosage adjustment necessary in elderly, renal or hepatic impairment

Interaction

  • Increased risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Possible occurrence of skin reactions, glossitis, heartburn, dizziness, tightness in the chest, nausea, vomiting, diarrhea, abdominal pain, vaginitis, candida overgrowth
  • Rare blood and lymphatic system disorders
  • Rare immune system disorders
  • Rare psychiatric disorders
  • Rare nervous system disorders
  • Rare hepatobiliary disorders
  • Rare renal and urinary disorders
  • Unknown investigation results

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised for lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result with certain tests
  • Lactose content
  • Dosage adjustment necessary in renal impairment

Use in Special Populations

  • Dosing recommendations for patients with renal impairment
  • Additional information for all patients
  • Restriction on pediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Need for supportive treatment
  • Possibility of gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Limited shelf life of reconstituted suspension
  • Limited shelf life of injection solutions
  • Color variation in reconstituted solutions
  • Do not use later than the date of expiry
  • Keep out of reach of children

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