Glovocef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Globex pharmaceuticals ltd
Also available as
Glovocef 500 mg capsule

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptibility of microorganisms
  • Susceptibility to different strains of bacteria

Pharmacology

  • Cephradine as a broad spectrum bactericidal antibiotic
  • Activity against gram-positive and gram-negative microorganisms
  • Sensitivity to Cephradine in both penicillinase producing and nonproducing staphylococci
  • Inhibition of cross-linking process in the cell wall of bacteria

Dosage & Administration

  • Adult dosage recommendations for different infections
  • Children dosage recommendations for different infections
  • Elderly patient dosage considerations
  • Dosage and administration for injectable use

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Cephradine contraindicated in known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Occasional skin reactions
  • Rare side effects like glossitis, heartburn, dizziness, nausea, vomiting, diarrhea, renal disorders
  • Rare immune system and psychiatric disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion of Cephradine in breast milk
  • Caution in lactating mothers
  • Caution regarding operating hazardous machinery

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administer with care to patients hypersensitive to penicillins
  • Potential positive result in Coombs’ testing
  • Possibility of false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content caution

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Dosing recommendations for patients on chronic, intermittent haemodialysis
  • Need for regular bacteriological and clinical monitoring in chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms of overdose
  • Supportive treatment
  • Necessity of gastric lavage in case of large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly preparation of Glovocef Suspension
  • Reconstituted Suspension usage timeline
  • Usage timeline for Glovocef Injection solutions
  • Solutions potency retention under different storage conditions
  • Guidelines for dispensing and storage of the medicine

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