Indocef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Indo bangla pharmaceutical

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibit cross-linking process in bacterial cell wall

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Maximum daily dosage
  • Dosage for injectable administration in adults
  • Dosage for injectable administration in children
  • Dosage adjustment in renal impairment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Limited to gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and serum creatinine
  • Elevation of liver enzyme disturbances

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to penicillin-hypersensitive patients
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommended doses for patients not on haemodialysis
  • Recommended doses for patients on chronic, intermittent haemodialysis
  • Higher doses required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required in urinary tract infections

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, and diarrhea
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Use reconstituted Suspension within 7-14 days
  • Use injection solutions within 2 hours at room temperature
  • Retain potency of solutions for 12 hours at 5°C
  • Variation in color of reconstituted solutions does not affect potency
  • Dispensed only on prescription of registered physician

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