Sporin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Marksman pharmaceuticals ltd
Also available as
Sporin 500 mg capsule Sporin 125 mg pediatric drop

Title

  • Sporin (Generic Name: Cephradine)

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Description

  • Broad spectrum bactericidal antibiotic
  • For the treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • For oral and injectable administration

Size

Various dosages available for different age groups and severities of infection

Color Options

N/A

Active Ingredient

  • Cephradine

Site of Action

Cell wall of bacteria

Bacterial Susceptibility

  • Sensitive Gram-positive and Gram-negative bacteria
  • Penicillin sensitive and resistant strains and penicillinase-producing species

Dosage Forms

  • Oral tablets
  • Injectable solutions

Dosage Range

From 250mg to 4g depending on age and severity of infection

Route of Administration

  • Oral
  • Injectable (Intramuscular or Intravenous)

Interaction

  • Potential nephrotoxicity when used concomitantly with aminoglycosides
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood disorders
  • Liver and kidney effects
  • Immune system reactions

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk, caution in lactating mothers

Precautions & Warnings

  • Potential for superinfection with prolonged use
  • Care with patients hypersensitive to penicillins
  • Positive Coombs’ testing
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose, not suitable for certain hereditary conditions

Use in Special Populations

  • Special dosing recommendations for patients with renal impairment
  • Paediatric dosages should not exceed those for adults

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Treatment is mainly supportive

Therapeutic Class

First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions retain potency for 2-12 hours
  • Dispensed only on prescription

Pharmacological Mechanism

  • Inhibits cross-linking of peptidoglycan in bacterial cell wall
  • Leads to formation of cell wall with pores causing bacterial lysis

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