Mefrad 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 100.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Modern pharmaceuticals ltd
Also available as	Mefrad 500 mg capsule

Indications

Treatment of upper respiratory tract infections
Treatment of lower respiratory tract infections
Treatment of urinary tract infections
Treatment of skin and soft tissue infections
Susceptibility of microorganisms to Mefrad

Pharmacology

Broad spectrum bactericidal antibiotic
Active against gram-positive and gram-negative microorganisms
Inhibition of cross-linking process in cell wall
Lysis of bacteria due to external osmotic pressure

Dosage & Administration

Oral administration dosages for adults and children
Maximum daily dosage
Injectable administration dosages for adults and children
Dosage adjustment in renal impairment

Interaction

Concomitant use of nephrotoxic drugs
Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

Hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Various rare side effects

Pregnancy & Lactation

Teratogenicity in animal studies not established
Excretion in breast milk
Caution in lactating mothers

Precautions & Warnings

Development of superinfection with prolonged use
Risk of cross-sensitivity between beta-lactam antibiotics
Potential for false positive urine glucose result
Lactose content and intolerance precautions

Use in Special Populations

Recommended doses for patients with renal impairment
Additional information for all patients

Overdose Effects

Non-specific symptoms
Supportive treatment
Necessity of gastric lavage

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Fresh preparation of suspension
Duration of usability for reconstituted solution
Potency retention under specific temperature conditions
Dispensing only on prescription

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