Catopil 25 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Captopril
Company Zenith pharmaceuticals ltd

Indications

  • Mild-to-moderate hypertension
  • Severe hypertension
  • Congestive heart failure

Pharmacology

  • Sulfhydryl-containing analog
  • Antihypertensive activity
  • Competitively inhibits ACE
  • Decreases levels of angiotensin II
  • Increases plasma renin activity
  • Decreases aldosterone secretion
  • Rapid absorption from GI tract
  • Renally excreted

Dosage & Administration

  • Initial dose for mild-to-moderate hypertension: 12.5 mg twice daily
  • Usual maintenance dose for mild-to-moderate hypertension: 25mg twice daily
  • Maximum dose for mild-to-moderate hypertension: 50 mg twice daily
  • Starting dose for severe hypertension: 12.5 mg twice daily
  • Maximum dose for severe hypertension: 50 mg three times daily
  • Starting dose for heart failure: 6.25mg or 12.5mg
  • Usual maintenance dose for heart failure: 25mg three times a day
  • Maximum dose for heart failure: 150 mg daily
  • Must be taken 1 hour before meals
  • Not established for pediatric patients

Interaction

Do not coadminister aliskiren with Catopil in patients with diabetes. Monitor renal function periodically.

Contraindications

  • Hypersensitivity to captopril
  • Contra-indicated in pregnancy
  • Not for use in women of child-bearing potential

Side Effects

  • Neutropenia
  • Anaemia
  • Proteinuria
  • Hypotension
  • Tachycardia
  • Pruritic rashes
  • Gastric irritation
  • Abdominal pain

Pregnancy & Lactation

No available data in pregnant women. Decision should be made whether to discontinue nursing or to discontinue the drug.

Precautions & Warnings

  • Assessment of renal function before therapy
  • Not for use in patients with renal impairment
  • Not for use in patients with aortic stenosis or outflow tract obstruction

Overdose Effects

Correction of hypertension

Therapeutic Class

Angiotensin-converting enzyme (ACE) inhibitors

Storage Conditions

Keep below 30°C, away from light & moisture, out of the reach of children

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