Cildip 10 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 14: ৳ 420.00)

Strip Price: ৳ 140.00

Medicine Details

Category	Details
Generic	Cilnidipine
Company	Opsonin pharma ltd
Also available as	Cildip 5 mg tablet

Indications

Management of hypertension for end-organ protection
Useful in elderly patients and those with diabetes and albuminuria
Use in patients with chronic kidney disease

Pharmacology

Dihydropyridine calcium-channel blocker
Binds to dihydropyridine binding sites of L-type voltage dependent calcium channel
Inhibits Ca2+ influx across cell membranes of vascular smooth muscle cells
Causes vasodilation
Inhibits Ca2+ influx via N-type voltage dependent calcium channels in sympathetic nerve cell membrane
Suppresses reflex increase in heart rate after blood pressure reduction

Dosage & Administration

Adult dose: 5-10 mg once daily after breakfast
Maximum adult dose: 20 mg once daily
Pediatric use safety not established
Initiate elderly therapy with lowest possible dose

Interaction

Other anti-hypertensive medications
Antipsychotics causing hypotension
Quinidine
Carbamazepine
Phenytoin
Rifampicin
Cimetidine
Erythromycin

Contraindications

Known sensitivity to Cilnidipine or excipients
Cardiogenic shock
Recent MI or acute unstable angina
Severe aortic stenosis

Side Effects

Dizziness
Flushing
Headache
Hypotension
Peripheral edema
Palpitations
GI disturbances
Increased micturition frequency
Lethargy
Eye pain
Depression

Pregnancy & Lactation

Not recommended for pregnant or nursing women
Discontinue lactation if administration is indispensable

Precautions & Warnings

Administer with care in patients with serious hepatic dysfunction
Administer with care in patients with a history of serious adverse reactions to calcium antagonists
Gradually decrease dosage during discontinuation under close observation

Therapeutic Class

Calcium-channel blockers

Storage Conditions

Store below 30°C
Protected from light and moisture
Keep away from reach of children

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