Cilnical 10 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Indications

  • Management of hypertension
  • End-organ protection
  • Elderly patients
  • Diabetes and albuminuria
  • Chronic kidney disease

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Inhibition of Ca2+ influx
  • Vasodilation
  • Inhibition of norepinephrine release
  • Suppression of reflex increase in heart rate

Dosage & Administration

  • Adults: 5-10 mg once daily after breakfast
  • Maximum dose: 20 mg once daily
  • Pediatric use safety not established
  • Initiation with lowest possible dose in elderly

Interaction

  • Other anti-hypertensive drugs
  • Antipsychotics causing hypotension
  • Quinidine
  • Carbamazepine
  • Phenytoin
  • Rifampicin
  • Cimetidine
  • Erythromycin

Contraindications

  • Known sensitivity to Cilnidipine or excipients
  • Cardiogenic shock
  • Recent MI
  • Acute unstable angina
  • Severe aortic stenosis

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Palpitations
  • GI disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Depression

Pregnancy & Lactation

  • Not for pregnant women
  • Avoid in nursing mothers
  • Discontinue lactation if necessary

Precautions & Warnings

  • Care in patients with serious hepatic dysfunction
  • History of serious adverse reactions to calcium antagonists
  • Gradual dosage decrease during discontinuation

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store below 30°C
  • Protected from light and moisture
  • Keep away from children

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