Anapril 10 mg (Tablet)
Unit Price: ৳ 2.70 (10 x 10: ৳ 270.00)
Strip Price: ৳ 27.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Enalapril maleate |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Title
Anapril
Categories
- Hypertension Medication
- Heart Failure Medication
- ACE Inhibitor
Description
Anapril is indicated for essential hypertension, renovascular hypertension, symptomatic heart failure, congestive heart failure, prevention of coronary ischaemic events, angina, diabetic nephropathy, Raynaud's disease. It inhibits Angiotensin Converting Enzyme (ACE) and belongs to the therapeutic class of ACE inhibitors. The dosage varies for different indications and special populations. It has interactions and contraindications with specific medications and medical conditions. Side effects, precautions, pregnancy contraindication, and overdose effects are also noted.
Color Options
- White
Dimensions
Standard tablet size
Dosage Options
- Hypertension:
- 5mg once daily initially
- 10-20mg once daily maintenance dose
- Maximum 40mg once daily in severe hypertension
- Heart Failure:
- 2.5mg initially under medical supervision
- 20mg daily maintenance dose in 1-2 divided doses
Materials
- Enalapril
- Enalaprilate
Functions
- Inhibits ACE
- Lowers blood pressure
- Treats heart failure
- Prevents coronary events
- Treats angina and diabetic nephropathy
- Adjunct in congestive heart failure treatment
Technical Specifications
- Pharmacology: Inhibits ACE and suppresses the renin-angiotensin aldosterone system
- Pregnancy and Lactation Category: Category D (contraindicated in pregnancy)
Design Elements
- Packaging: Blister pack
- Tablet Shape: Round
Usability Features
- Elderly-effective dose starts at 2.5mg
- Regular WBC counts recommended for certain patients
Side Effects
- Dizziness
- Headache
- Fatigue
- Asthenia
- Hypotension
- Nausea
- Diarrhoea
- Renal dysfunction
- Rash
- Cough
Contraindications
- Medical Conditions:
- Aortic stenosis
- Renovascular disease
- Severe resistant HTN
- Peripheral vascular disease or generalized atherosclerosis
Interaction
- Positive Interactions:
- Combination with b blockers, Methyldopa, calcium antagonists, and diuretics
- Adverse Interaction:
- Concomitant therapy with Lithium may increase the serum Lithium concentration
Pregnancy and Lactation
- Excretion: Excreted in trace amount in human milk
Precautions and Warnings
- Assessment of renal function recommended
- Regular WBC counts in patients with collagen vascular disease
- Caution in patients prone to salt or water depletion
- Pregnancy caution
Use in Special Populations
- Elderly: Effective starting dose at 2.5mg; titrate according to need for blood pressure control
Overdose Effects
- Symptoms:
- Lightheadedness
- Decrease in urine output
- Drowsiness
- Slow or irregular heartbeat
- Management:
- Fluids through an intravenous line (IV)
- Medications to increase blood pressure
- Close heart and lung monitoring