Tofacit 5 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 10: ৳ 300.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Delta pharma ltd |
| Also available as |
Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ulcerative Colitis
Pharmacology
Autoimmune disease, cytokine dysregulation, JAK signaling pathway, inflammation
Dosage & Administration
- Recommended dosage in renal impairment
- Recommended dosage in hepatic impairment
- Discontinue dosage after 16 weeks if no therapeutic benefit is achieved
Interaction
- Potent inhibitors of CYP3A4
- Moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
- Potent CYP inducers
Side Effects
- Upper respiratory tract infections
- Headache
- Diarrhea
- Nasopharyngitis
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in human milk
- Potential risk to the fetus
- Discontinuation of nursing
Precautions & Warnings
- Avoid use during active serious infection
- Caution in patients at risk of gastrointestinal perforations
- Laboratory monitoring for lymphocytes, neutrophils, hemoglobin, liver enzymes, and lipids
- Avoid live vaccines
- Do not initiate if absolute lymphocyte count <500 cells/mm3
Use in Special Populations
- Pediatric use not established
- Higher incidence of infections in the elderly population
- Dosage in renal and hepatic impairment
Therapeutic Class
Immunosuppressant
Storage Conditions
Store below 30°C, protect from light and moisture