Tocit XR 11 mg (Tablet (Extended Release))
Unit Price: ৳ 75.00 (1 x 14: ৳ 1,050.00)
Strip Price: ৳ 1,050.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of rheumatoid arthritis
- Treatment of psoriatic arthritis
- Treatment of ulcerative colitis
Pharmacology
- Autoimmune disease characterized by dysregulation of pro-inflammatory cytokines
- Tofacitinib is a partial and reversible janus kinase (JAK) inhibitor
- Inhibits JAK-STAT signaling pathway
- Decreases inflammatory response
Dosage & Administration
- Tofacitinib 5mg twice daily
- Tofacitinib 11mg once daily
- Recommended dosages for different conditions
Interaction
- Interactions with Cytochrome P450 3A4 (CYP3A4)
- Effects of CYP inhibitors and inducers
Side Effects
- Common adverse reactions reported in clinical trials
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if benefits outweigh risks
- Potential excretion in human milk
Precautions & Warnings
- Avoid use during serious infections
- Use with caution in patients at risk of gastrointestinal perforations
- Recommended laboratory monitoring
- Avoid use with live vaccines
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Higher frequency of serious infection in elderly population
- Dosage adjustment for renal and hepatic impairment
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children