Tofatin 5 mg (Tablet)
Unit Price: ৳ 45.00 (1 x 10: ৳ 450.00)
Strip Price: ৳ 450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ulcerative Colitis
Pharmacology
Inhibits pro-inflammatory cytokines and janus kinase signalling pathway
Dosage & Administration
- Rheumatoid Arthritis:
- 5 mg twice daily
- 11 mg once daily
- Psoriatic Arthritis:
- 5 mg twice daily
- 11 mg once daily
- Ulcerative Colitis: 10 mg twice daily for 8 weeks, then 5 or 10 mg twice daily
Interactions
- Cytochrome P450 3A4 inhibitors
- CYP2C19 inhibitors
- Potent CYP inducers
Side Effects
- Upper respiratory tract infections
- Headache
- Diarrhea
- Nasopharyngitis
Pregnancy & Lactation
Pregnancy Category C, potential risk to the fetus
Precautions & Warnings
- Serious Infections: Avoid use during active serious infection
- Gastrointestinal Perforations: Use with caution
- Laboratory Monitoring: Recommended for potential changes in various blood parameters
- Immunizations: Avoid use with live vaccines
- Absolute Counts: Do not initiate if lymphocyte count, neutrophil count, or hemoglobin levels are low
Use in Special Populations
- Pediatric Use: Safety and effectiveness not established
- Geriatric Use: Higher incidence of infections, caution in elderly
- Renal & Hepatic Impairment: Adjusted dosage
Therapeutic Class
Immunosuppressant
Storage Conditions
Store below 30°C, protect from light and moisture