Pulmosis 267 mg (Capsule)
Unit Price: ৳ 45.00 (3 x 10: ৳ 1,350.00)
Strip Price: ৳ 450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pirfenidone |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title and Category
- Pulmosis Medicine
- IPF Treatment
- Immunosuppressant Drug
Dosage & Administration
- Oral administration
- Dosage titration over 14 days
- Recommended daily dose of 2403 mg/day
- Dose adjustment for gastrointestinal event
- Dose adjustment for photosensitivity reaction or rash
- Dose adjustment for hepatic function
- Missed dose recommendation
Indications
- Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF) in adults
Pharmacology
- Anti-inflammatory properties
- Antioxidant properties
- Anti-fibrotic properties
- Improvement of lung function
- Reduction of acute exacerbations in IPF patients
- Suppression of TGF-β1
- Downregulation of pro-inflammatory cytokines
Interaction
- Moderate and strong inhibitors of CYP1A2 increase systemic exposure
- Dosage adjustment with specific medicines
- Reduced incidence of adverse reactions in fed group
Contraindications
- Hypersensitivity to active substance or excipients
- Concomitant use of fluvoxamine
- Severe hepatic impairment or end stage liver disease
- Severe renal impairment or end stage renal disease
Side Effects
- Common: nausea, rash, abdominal pain, upper respiratory tract infection, and more
- Rare: photosensitivity reaction, decreased appetite, pruritus, asthenia, and more
Pregnancy & Lactation
- Precaution during pregnancy
- Precaution during lactation
- Effect on fertility in rats
Precautions & Warnings
- Elevated liver enzymes
- Photosensitivity and rash
- Gastrointestinal disorders
Uses in Special Populations
- Safety and effectiveness in children & adolescents
- Monitoring in hepatic impairment
- Monitoring in renal impairment
- Effect on smokers
Overdose Effects
- Limited clinical experience with overdose
- Mild and transient adverse reactions
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store in cool & dry place
- Protect from light & moisture
- Keep out of reach of children