Candinil 200 mg (Capsule)

Unit Price: ৳ 25.00 (3 x 4: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Fluconazole
Company Healthcare pharmaceuticals ltd
Also available as
Candinil 50 mg capsule Candinil 150 mg capsule Candinil 50 mg suspension

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Superficial Candidiasis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Potent inhibitor of fungal cytochrome P-450 dependent enzymes

Dosage & Administration

  • Adults:
    • Vaginal Candidiasis: 150 mg as a single dose
    • Oropharyngeal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14 days
    • Oesophageal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14-30 days
    • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea: 150 mg weekly for 4-6 weeks
    • Kerion: 50 mg daily for 20 days
    • Pityriasis versicolor: 400 mg as a single dose
    • Onychomycosis: 150 mg weekly for 12 months
    • Invasive candidal infections and cryptococcal infections (including meningitis): Orally or by IV infusion, 400 mg on first day then 200-400 mg daily
    • Prevention of cryptococcal meningitis: Orally or by IV infusion 200 mg daily
    • Prevention of fungal infections in immunocompromised patients: Orally or by IV infusion, 50-400 mg daily
  • Child over 1 year:
    • In Superficial Candidiasis: 1-2 mg/kg daily
    • In Systemic Candidiasis & Cryptococcal infection:3-6 mg/kg daily
  • Use in Specific Population:
    • Elderly patient: The normal dose should be used if there is no evidence of renal impairment
    • Renal Impairment: Dosage interval should be modified based on creatinine clearance

Interaction

  • Interaction with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptive, cyclosporin, food, cemetidine, antacids, theophylline, other medications

Contraindications

Known hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Flatulence
  • Rash (Incidence less than 1%)
  • Anaphylaxis

Pregnancy & Lactation

Not recommended in pregnancy or in women of childbearing potential unless adequate contraception is employed

Precautions & Warnings

  • Abnormalities of hepatic, renal, haematological, and other biochemical function tests observed in some patients
  • Rare cases of hepatic necrosis
  • Exfoliative cutaneous reactions observed rarely
  • Use in lactation not recommended

Use in Special Populations

  • Elderly: Normal dose should be used if there is no evidence of renal impairment
  • Renal impairment: Dosage intervals or daily dosage should be modified based on creatinine clearance

Overdose Effects

Supportive measures and symptomatic treatment recommended

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children

Related Brands