Esoral MUPS 20 mg (MUPS Tablet)

Unit Price: ৳ 10.00 (5 x 12: ৳ 600.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Esomeprazole mups preparation
Company Eskayef pharmaceuticals ltd
Also available as
Esoral mups 40 mg tablet

Title

  • Esoral MUPS Tablet

Categories

  • Pharmaceuticals
  • Medicine
  • Gastrointestinal Health

Description

  • Indicated for Gastro-esophageal Reflux Disease (GERD)
  • Used for risk reduction in NSAID associated gastric ulcer
  • Effective in H. pylori eradication (Triple therapy)
  • Suitable for Zollinger-Ellison syndrome and idiopathic hypersecretion
  • Contains Esomeprazole MUPS 20 Tablet and Esomeprazole MUPS 40 Tablet

Composition

  • Contains Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole
  • Also contains Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole

Indications

  • Treatment of Gastro-esophageal Reflux Disease (GERD)
  • Reduction of risk associated with NSAID gastric ulcer
  • H. pylori eradication
  • Management of Zollinger-Ellison syndrome and idiopathic hypersecretion

Pharmacology

  • Inhibits gastric acid by blocking the hydrogen-potassium adenosine triphosphatase enzyme system
  • Effective for short-term treatment of gastric and duodenal ulcers
  • Used for prevention and treatment of NSAID associated gastric ulcers

Dosage

  • Adult dosage for erosive esophagitis: 40 mg once daily for 4 weeks
  • Adult dosage for maintenance of healing of erosive esophagitis: 20 mg once daily
  • Adult dosage for risk reduction in NSAID associated gastric ulcer: 20 mg once daily for 4-8 weeks
  • Adult dosage for H. pylori eradication: 20 mg twice daily for 7 days
  • Adult dosage for Zollinger-Ellison syndrome and idiopathic hypersecretion: 40-80 mg twice daily
  • Children dosage for erosive esophagitis: Weight <20 kg: 10 mg once daily for 8 weeks, Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks
  • Children dosage for maintenance of healing of erosive esophagitis: 10 mg once daily
  • Not approved for use in children younger than 1 year

Administration

  • Tablets should be swallowed whole with liquid
  • Tablets should not be chewed or crushed
  • Can be dispersed in half a glass of non-carbonated water if required

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
  • May interfere with the absorption of drugs where gastric pH is important for bioavailability

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth

Pregnancy & Lactation

  • Manufacturer advises caution as it is not known if Esomeprazole or its metabolites appear in human breast milk

Precautions & Warnings

  • Should be used carefully in patients with severe liver dysfunction and severe renal impairment
  • May slightly increase the risk of hip, wrist, and spine fracture over a period of more than one year

Storage Conditions

  • Store in a cool and dry place below 25°C
  • Protect from light
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure available

Common Questions

  • What is Esoral MUPS 20 mg MUPS Tablet?
  • What is MUPS Tablet?
  • What is Esoral MUPS 20 mg MUPS Tablet used for?
  • What are the side effects of Esoral MUPS 20 mg MUPS Tablet?
  • Can I take Esoral MUPS 20 mg MUPS Tablet if I am pregnant or breastfeeding?
  • How long does it take for Esoral MUPS 20 mg MUPS Tablet to work?
  • Quick Tips available for usage

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