Opton 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Beximco pharmaceuticals ltd
Also available as
Opton 20 mg tablet Opton 40 mg tablet Opton 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related dyspepsia
  • Treatment of duodenal and gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage ranges for different indications
  • Different dosages for adults and pediatric patients
  • Dosage reduction for severe hepatic insufficiency

Administration

  • Tablet or capsule form administration
  • Oral suspension administration
  • IV Injection administration
  • Instructions for administration through a nasogastric or gastric tube
  • Preparation of IV injection solution

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific CYP enzymes
  • Interference with the absorption of specific drugs
  • Co-administration effects with clarithromycin

Contraindications

  • Contraindicated in patients with known hypersensitivity to the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • Similar adverse events during maintenance and short-term treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if esomeprazole use is essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients who have difficulty swallowing capsules
  • Use of antacids during Opton administration

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy between the elderly and younger individuals
  • No dosage adjustment for patients with mild to moderate hepatic insufficiency
  • No alteration of pharmacokinetics in patients with renal impairment

Overdose Effects

  • Toxicity effects observed in rats
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry and protected from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure available as an image

Common Questions about Opton 20 mg Capsule

  • Information about Opton 20 mg Capsule
  • Multiple uses of Opton 20 mg Capsule
  • Common side effects of Opton 20 mg Capsule
  • Use of Opton 20 mg Capsule during pregnancy and breastfeeding
  • Onset of action of Opton 20 mg Capsule
  • Quick tips for using Opton 20 mg Capsule

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