Xelpro 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 8.00 (10 x 10: ৳ 800.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Pharmasia limited |
| Also available as |
Title
- Xelpro 20 mg Capsule
Categories
- Medicine
- Gastrointestinal Health
- Pharmaceutical
Description
- Proton pump inhibitor for relieving chronic heartburn and GERD symptoms
- Healing of erosive esophagitis and maintenance
- For Helicobacter pylori eradication in combination with antibiotics
- Treatment of Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers
Color Options
- None
Dosage Form
- Tablet
- Capsule
- Oral Suspension
- IV Injection
- IV Infusion
Dosage Strengths
- 20 mg
- 40 mg
- 80 mg (intravenous)
Administration
- Oral administration one hour before meals
- Swallowing whole tablets or capsules
- Preparation of oral suspension
- Preparation and administration of IV injection
- Duration and dosage for different conditions
Pharmacology
- Proton pump inhibitor
- Specific inhibition of H⁺/K⁺-ATPase
- Enteric-coated pellet formulation
- Absorption, distribution, metabolism, and excretion details
- Combination therapy with antimicrobials
- Peak plasma levels and elimination half-life
Interaction
- Metabolism by CYP2C19 and CYP3A4
- Inhibition of gastric acid secretion
- Possible interference with drug absorption based on gastric pH
- Specific drug interaction studies with phenytoin, warfarin, quinidine, clarithromycin, and amoxicillin
- Potential interference with absorption of drugs influenced by gastric pH
Contraindications
- Hypersensitivity to any formulation
Indications
- Relief from chronic heartburn and GERD symptoms
- Healing and maintenance of erosive esophagitis
- Helicobacter pylori eradication with antibiotics
- Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers
Side Effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
- No difference in side effects during maintenance treatment
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Excretion in milk not studied, breastfeeding to be discontinued if essential
Precautions & Warnings
- Symptomatic response does not rule out gastric malignancy
- Instructions for patients with difficulty swallowing capsules
- Use of antacids during treatment
Special Populations
- Safety and efficacy not established in pediatric patients
- No overall differences in safety and efficacy observed in geriatric patients
- No dosage adjustment for mild to moderate hepatic insufficiency
- Unlikely alteration in pharmacokinetics for renal impairment
Overdose Effects
- Lethal dose in rats
- Signs of acute toxicity
- No specific antidote known
- Management should be symptomatic and supportive
Storage Conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Common Questions
- Overview of Xelpro 20 mg Capsule
- Uses and side effects
- Safety during pregnancy and breastfeeding
- Onset of action and quick tips for usage