Exilok 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (9 x 10: ৳ 630.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Osl pharma limited
Also available as
Exilok 40 mg capsule Exilok 20 mg tablet Exilok 40 mg tablet Exilok 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Single optical isomer of proton pump inhibitor
  • Enteric-coated pellet formulation
  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Extensively metabolized in the liver
  • High plasma protein binding
  • Excreted as inactive metabolites in urine and faeces

Dosage

  • Oral dosage form
  • IV Injection or IV infusion for specific conditions
  • Dosage varies for different indications

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with specified water volume and method
  • IV Injection requires specific preparation and administration procedure

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs
  • Potential interference with gastric pH-dependent drug absorption

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • No significant difference in adverse events during maintenance treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies showed no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Special instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking the medication

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • No overall differences in safety and efficacy in the elderly
  • No dosage adjustment for patients with mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • Lethal dose observed in animal studies
  • Major signs of acute toxicity
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protected from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure provided in an image format

Common Questions

  • What is Exilok 20 mg Capsule?
  • What is Exilok 20 mg Capsule used for?
  • What are the side effects of Exilok 20 mg Capsule?
  • Can I take Exilok 20 mg Capsule if I am pregnant or breastfeeding?
  • How long does it take for Exilok 20 mg Capsule to work?
  • Quick Tips for taking Exilok 20 mg Capsule

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