Esobest 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sharif pharmaceuticals ltd
Also available as
Esobest 20 mg capsule Esobest 40 mg capsule Esobest 40 mg tablet Esobest 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of duodenal & gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Metabolized by the CYP enzyme system
  • 97% bound to plasma proteins
  • Plasma elimination half-life of approximately 1–1.5 hours
  • Excretion of less than 1% in urine

Dosage

  • 20 mg or 40 mg once daily for healing of erosive esophagitis
  • 20 mg once daily for maintenance of healing of erosive esophagitis
  • 20 mg once daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for duodenal ulcer
  • 20-40 mg once daily for 4-8 weeks for gastric ulcer
  • IV Injection or IV infusion dosages

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension instructions
  • IV injection preparation and administration

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Inhibition of gastric acid secretion affecting drug absorption
  • No clinically significant interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No excretion data in milk
  • Breast-feeding discontinuation if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients with swallowing difficulties
  • Allowable use of antacids while taking Esobest

Use in Special Populations

  • No established safety and effectiveness in paediatric patients
  • No overall differences in safety and efficacy in the elderly
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • Unaltered pharmacokinetics in patients with renal impairment

Overdose Effects

  • Acute toxicity signs in animal studies
  • No specific antidote known
  • Symptomatic and supportive treatment required

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure image

Common Questions about Esobest 20 mg Tablet

  • Description of Esobest 20 mg Tablet and its uses
  • Common side effects of Esobest 20 mg Tablet
  • Guidance for pregnant or breastfeeding individuals
  • Onset of action for Esobest 20 mg Tablet
  • Quick tips for using Esobest 20 mg Tablet

Related Brands