Esotron 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.50 (3 x 10: ৳ 164.88)
Strip Price: ৳ 54.96

Medicine Details

Category Details
Generic Esomeprazole
Company Jayson pharmaceuticals ltd
Also available as
Esotron 40 mg tablet

Title

  • Esotron 20 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Proton pump inhibitor for treating GERD and related symptoms

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Symptomatic relief for Acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Better acid control with single optical isomer
  • Specific inhibition of the H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Absorption peaks at approximately 1.5 hours
  • Extensively metabolized in the liver

Dosage

  • Oral dosage form
  • Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
  • Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
  • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
  • Helicobacter Pylori eradication: Esomeprazole 40 mg Once Daily for 10 days
  • Zollinger-Ellison Syndrome: 20-80 mg once daily
  • Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks
  • Duodenal ulcer: 20 mg once daily for 2-4 weeks
  • IV Injection/infusion also available for certain conditions

Administration

  • Tablets or capsules to be swallowed whole before a meal
  • Oral suspension to be taken with water or administered through a tube
  • IV injection solution for intravenous administration
  • Specific instructions for nasogastric or gastric tube administration

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific CYP enzymes
  • May interfere with absorption of drugs impacted by gastric pH

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side effects

  • Common adverse events: headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth

Pregnancy lactation

  • No adequate studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions warnings

  • Response to therapy does not preclude presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • May be used with antacids

Special populations

  • Safety and effectiveness not established in paediatric patients
  • No overall differences in safety and efficacy observed between elderly and younger individuals

Overdose effects

  • Single oral dose at 510 mg/kg lethal to rats
  • Major signs of toxicity include reduced motor activity, respiratory frequency changes, tremor, ataxia, and convulsions
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure provided

Common questions

  • What is Esotron 20 mg Tablet?
  • Uses of Esotron 20 mg Tablet
  • Common side effects of Esotron 20 mg Tablet
  • Use of Esotron 20 mg Tablet during pregnancy or breastfeeding
  • Time taken for Esotron 20 mg Tablet to work
  • Quick tips for using Esotron 20 mg Tablet

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