Epizol 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (6 x 10: ৳ 420.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Nipa pharmaceuticals ltd
Also available as
Epizol 40 mg capsule

Title

  • Epizol 20 mg Capsule

Categories

  • Medicine
  • Gastric Acid Reducer
  • Proton Pump Inhibitor
  • Gastrointestinal Medication

Description

  • Relieves chronic heartburn symptoms
  • Heals erosive esophagitis
  • Treats symptoms associated with GERD
  • Eradicates Helicobacter pylori infection
  • Manages Zollinger-Ellison Syndrome and acid-related Dyspepsia
  • For duodenal and gastric ulcer healing

DosageForm

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection
  • IV Infusion

DosageInstructions

  • 20 mg or 40 mg Once Daily for 4-8 Weeks for Healing of Erosive Esophagitis
  • 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • 40 mg Once Daily for Helicobacter Pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia
  • 20 mg Once Daily for Duodenal Ulcer & 20-40 mg Once Daily for Gastric Ulcer
  • IV Injection or IV Infusion for different age groups

Administration

  • Swallow whole, taken one hour before a meal for Tablet or Capsule
  • Mix with water and drink within 30 minutes for Oral Suspension
  • Intravenous administration over at least 3 minutes for IV Injection
  • Store at a temperature not exceeding 30°C in a dry place for Storage Conditions

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Single optical isomer provides better acid control
  • Absorption, Distribution, Metabolism, Excretion details

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Inhibits gastric acid secretion
  • Potential interference with CYP2C19
  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • Excretion of esomeprazole in milk not studied
  • Breast-feeding should be discontinued if use is essential

PrecautionsAndWarnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients regarding capsule intake and use of antacids

UseInSpecialPopulations

  • Safety and effectiveness in paediatric patients not established
  • No overall differences in safety and efficacy observed between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

OverdoseEffects

  • Toxicity signs in rats
  • No specific antidote known
  • Treatment should be symptomatic and supportive

StorageConditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

  • Molecular Formula: C17H19N3O3S

CommonlyAskedQuestions

  • Purpose of Epizol 20 mg Capsule
  • Uses and side effects
  • Use during pregnancy and breastfeeding
  • Onset time for action

AdditionalInformation

  • No difference in types of related adverse events between short term and maintenance treatment
  • No reports of overdose with Epizol

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