Esmosec 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (4 x 10: ৳ 200.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Techno drugs ltd
Also available as
Esmosec 40 mg injection Esmosec 40 mg tablet

Title

  • Esmosec 20 mg Tablet

Categories

  • Medicine
  • Health & Wellness

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Inhibition of H+/K+-ATPase
  • Single optical isomer for better acid control
  • Enteric-coated pellet formulation
  • Peak plasma levels at 1.5 hours
  • Metabolism by CYP enzyme system
  • Plasma protein binding of 97%
  • Excretion in urine and faeces

Dosage

  • 20 mg or 40 mg Once Daily for healing of erosive esophagitis
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • 40 mg Once Daily for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for acid-related Dyspepsia
  • 20 mg once daily for duodenal ulcer
  • 20-40 mg once daily for gastric ulcer
  • IV Injection or IV infusion for specific conditions

Administration

  • Swallow whole one hour before a meal for tablet or capsule
  • Preparation of oral suspension
  • Reconstitution and IV administration for injection

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • No clinically significant interactions with specific drugs
  • Potential interference with CYP2C19 and gastric pH-dependent drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied

Precautions & Warnings

  • Symptomatic response does not preclude gastric malignancy
  • Specific instructions for capsule administration
  • Use of antacids during treatment

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No noticeable differences in the elderly
  • Limited dosage adjustment for hepatic insufficiency
  • Unaltered pharmacokinetics in renal impairment

Overdose Effects

  • Lethal dose in rats
  • Signs of acute toxicity
  • No specific antidote known
  • Symptomatic and supportive treatment

Storage Conditions

  • Temperature not exceeding 30°C
  • Protection from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Commonly Asked Questions

  • Definition and usage of Esmosec 20 mg Tablet
  • Common side effects
  • Usage during pregnancy and lactation
  • Onset of action
  • Quick tips for use

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