Gaspro 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.35 (5 x 10: ৳ 317.50)
Strip Price: ৳ 63.50

Medicine Details

Category Details
Generic Esomeprazole
Company Ethical drugs limited
Also available as
Gaspro 40 mg capsule Gaspro 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Treatment of symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome relief
  • Treatment of acid-related Dyspepsia
  • Management of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Absorption peak at approximately 1.5 hours
  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Low plasma elimination half-life
  • Extensive metabolism in the liver
  • Excretion mainly in inactive metabolites

Dosage

  • Oral and IV administration
  • Different dosages for various conditions
  • Dosage form: Tablet, capsule, and oral suspension
  • IV Injection: Administration guidelines

Administration

  • Tablet or capsule to be swallowed whole
  • Oral suspension administration instructions
  • IV Injection preparation and guidelines

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interference with CYP2C19
  • Possible hindrance in drug absorption due to gastric pH alteration
  • Drug interaction with clarithromycin and amoxicillin

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients' ease of swallowing capsules
  • Usage of antacids while taking Gaspro

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No observed differences in safety and efficacy with geriatric use
  • No dosage adjustment in mild to moderate hepatic insufficiency
  • No expected alteration in pharmacokinetics in renal impairment

Overdose Effects

  • Lethal to rats at high doses
  • Major signs of acute toxicity
  • No specific antidote known

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure diagram available

Common Questions about Gaspro 20 mg Capsule

  • Purpose of Gaspro 20 mg Capsule
  • Multiple uses of Gaspro 20 mg Capsule
  • Common side effects
  • Safety during pregnancy or breastfeeding
  • Onset of action
  • Quick tips for usage

Related Brands