Bisocam 2.5 mg+5 mg (Tablet)

Indications

• Treatment of hypertension
• Substitution therapy
• Controlled blood pressure
• Combination therapy
• Separate tablets administration

Pharmacology

• Amlodipine calcium antagonist
• Bisoprolol selective adrenoceptor blocking agent
• Vascular smooth muscle inhibition
• Reduction in peripheral vascular resistance
• Inhibition of calcium ion influx

Dosage & Administration

• Once daily administration
• Fixed-dose combination
• Same doses for monocomponent products

Interaction

• Combinations not recommended
• Combinations to be used with caution
• Combinations to be considered
• CYP3A4 inhibitors and inducers
• Drug interactions
• Blood pressure lowering potential

Contraindications

• Acute heart failure
• Obstruction of left ventricle outflow tract
• AV block
• Sick sinus syndrome
• Severe bronchial asthma
• Peripheral arterial occlusive disease
• Phaeochromocytoma
• Metabolic acidosis
• Hypersensitivity to bisoprolol or amlodipine

Side Effects

• Dizziness
• Headache
• Edema
• Nausea
• Palpitations
• Insomnia
• Visual disturbances
• Weakness
• Weight changes
• Allergic reactions

Pregnancy & Lactation

• Not recommended during pregnancy or lactation

Precautions & Warnings

• Heart failure
• Impaired hepatic function
• Obstructive airways diseases
• Bronchospasm
• Diabetes mellitus
• AV block
• Peripheral arterial occlusive disease
• Psoriasis history
• Thyrotoxicosis
• General anesthesia

Use in Special Populations

• Geriatric use
• Pediatric use not established
• Patients with Liver disease
• Patients with Kidney disease

Overdose Effects

• Bradycardia
• Hypotension
• Bronchospasm
• Acute cardiac insufficiency
• Hypoglycemia
• Peripheral vasodilation

Therapeutic Class

• Anti-hypertensive

Storage Conditions

• Dry place
• Temperature below 30°C
• Protection from light
• Keep out of reach of children

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