Lijenta-MX 2.5 mg+1000 mg (Tablet (Extended Release))

Unit Price: ৳ 17.00 (2 x 8: ৳ 272.00)

Strip Price: ৳ 136.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Nipro jmi pharma ltd
Also available as	Lijenta m 25 mg tablet Lijenta m 25 mg tablet Lijenta m 25 mg tablet Lijenta mx 5 mg tablet

Indications

Adjunct to diet and exercise
Improves glycemic control
Type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4
Increases active incretin hormones
Stimulates insulin release
Decreases glucagon secretion
Oral antihyperglycemic drug
Lowers plasma glucose
Decreases hepatic glucose production
Improves insulin sensitivity

Dosage & Administration

Individualized dosage
Maximum recommended dose: 2.5 mg Linagliptin/1000 mg Metformin Hydrochloride twice daily with meals
Gradual dose escalation
Immediate release and extended release tablet options
Dose initiation based on current treatment

Interactions

Cationic drugs interaction
Carbonic Anhydrase Inhibitors interaction
Inducers of P-glycoprotein and CYP3A4 Enzymes interaction
Drugs affecting glycemic control

Contraindications

Renal impairment
Metabolic acidosis
Hypersensitivity to Linagliptin or Metformin Hydrochloride

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy only if clearly needed
Caution during lactation

Precautions & Warnings

Lactic acidosis risk
Postmarketing reports of acute pancreatitis
Discontinuation for radiologic studies
Monitoring of Vitamin B12 levels
Symptoms and precautions for lactic acidosis
Instructions for alcohol, other medicines, counseling, travel, emergencies

Overdose Effects

Supportive measures for overdose
Limited dose-related clinical adverse reactions
Hypoglycemia and lactic acidosis risk with Metformin Hydrochloride overdose

Therapeutic Class

Oral hypoglycemic preparations

Storage Conditions

Cool & dry place below 30°C
Protected from light & moisture
Keep out of reach of children

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