Lijenta-MX 5 mg+1000 mg (Tablet (Extended Release))

Unit Price: ৳ 24.00 (2 x 8: ৳ 384.00)
Strip Price: ৳ 192.00

Medicine Details

Category Details
Generic Linagliptin metformin hydrochloride
Company Nipro jmi pharma ltd
Also available as
Lijenta m 25 mg tablet Lijenta m 25 mg tablet Lijenta m 25 mg tablet Lijenta mx 25 mg tablet

Title

  • Linagliptin & Metformin Combination Tablet

Categories

  • Medicine
  • Diabetes Management
  • Oral Hypoglycemic

Description

  • This product is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
  • It is a combination of Linagliptin and Metformin Hydrochloride which work synergistically to manage blood glucose levels.

DosageAndAdministration

  • Should be individualized based on effectiveness and tolerability.
  • Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals.
  • Dose escalation should be gradual to reduce gastrointestinal side effects associated with Metformin Hydrochloride use.

DosageForm

  • Immediate release tablet
  • Extended release tablet

MaximumRecommendedDose

  • 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
  • Maximum daily dose of Linagliptin 5 mg and Metformin Hydrochloride 2000 mg for extended release tablet.

Interaction

  • Potential interaction with cationic drugs, carbonic anhydrase inhibitors, inducers of P-glycoprotein and CYP3A4 enzymes, and drugs affecting glycemic control.

Contraindications

  • Contraindicated in patients with renal impairment, acute or chronic metabolic acidosis, and hypersensitivity to Linagliptin or Metformin Hydrochloride.

CommonSideEffects

  • Nasopharyngitis
  • Diarrhea

PregnancyAndLactation

  • Use during pregnancy only if clearly needed
  • Caution should be exercised when administered to a lactating mother.

PrecautionsAndWarnings

  • Discontinue if lactic acidosis is suspected
  • Monitor Vitamin B12 levels annually due to potential decrease from Metformin
  • Precautions related to alcohol, other medicines, counseling, travel, and emergencies
  • Potential for hypoglycemia

OverdoseEffects

  • Supportive measures should be employed in case of overdose
  • Hemodialysis or peritoneal dialysis is unlikely to remove Linagliptin but Metformin is dialyzable
  • No dose-related adverse drug reactions with Linagliptin up to 600 mg
  • Hypoglycemia and lactic acidosis reported in Metformin Hydrochloride overdose cases.

TherapeuticClass

  • Combination Oral hypoglycemic preparations

StorageConditions

  • Store in a cool & dry place (below 30°C)
  • Protect from light & moisture
  • Keep out of the reach of children

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