Pendoril 4 mg (Tablet)

Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Perindopril arginine
Company Renata limited
Also available as

Indications

  • Essential hypertension
  • Stable coronary artery disease
  • Congestive heart failure

Pharmacology

ACE inhibitor that works by blocking the action of angiotensin converting enzyme (ACE), reducing the production of angiotensin II and allowing blood vessels to relax and widen

Dosage & Administration

  • Recommended daily dosage of 4mg once daily for hypertension, can be increased to 8mg
  • Initial dose of 4mg once daily for stable coronary artery disease, can be increased to 8mg
  • Initial dose of 2mg for congestive heart failure, may be increased to 4mg

Interaction

May interact with diuretics, K supplements, K-sparing diuretics, ciclosporin, heparin, indometacin, lithium, aspirin, NSAIDs, antidiabetic agents, and gold (Na aurothiomalate)

Contraindications

Contraindicated in patients with hypersensitivity to Perindopril, management of hypertension in children, and during pregnancy & lactation

Side Effects

  • Rare: cough, fatigue, asthenia, headache
  • Less often: taste impairment, epigastric discomfort, nausea, abdominal pain, rash, reversible increase in blood urea and creatinine, proteinuria
  • Rarely: angioneurotic edema, decrease in hemoglobin, red cells, and platelets

Pregnancy & Lactation

Not recommended for use during pregnancy & lactation

Precautions & Warnings

  • Caution in renovascular hypertension, surgery/anesthesia, renal failure, symptomatic hypotension, diuretic-treated patients, combination with neuroleptics or imipramine-type drugs, and during serum lithium therapy

Therapeutic Class

Angiotensin-converting enzyme (ACE) inhibitors, Direct Renin Inhibitors

Storage Conditions

Store below 30°C, away from light & moisture, and out of the reach of children

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