Deflacort 6 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Systemic lupus erythematosus
- Dermatomyositis
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immune system chemicals release reduction
- Immunosuppressive action
Dosage & Administration
- Adults dose range: 3-120 mg/day
- Maintenance doses range: 3-18 mg/day
- Children's dose range: 0.25-1.5 mg/kg/day
- Alternate day administration
- Deflazacort withdrawal guidelines
Interaction
- Metabolism in the liver
- Maintenance dose adjustment with liver enzyme inducers or inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture risk
- Thromboembolism risk
Pregnancy & Lactation
- Placental crossing
- Corticosteroids' risk in pregnancy
- Excretion in breast milk
- Infant adrenal suppression risk
- Benefit of breastfeeding outweighs theoretical risk at lower doses
Precautions & Warnings
- Cardiac disease or congestive heart failure caution
- Hypertension caution
- Thromboembolic disorders caution
- Salt and water retention risk
- Potassium excretion risk
- Gastritis or esophagitis caution
- Diverticulitis caution
- Ulcerative colitis caution
- Diabetes mellitus caution
- Osteoporosis caution
- Myasthenia gravis caution
- Renal insufficiency caution
- Emotional instability or psychotic tendency caution
- Epilepsy caution
- Liver failure caution
- Hypothyroidism and cirrhosis caution
- Ocular herpes simplex caution
Use in Special Populations
- Hepatic Impairment considerations
- Renal Impairment considerations
- Elderly patients considerations
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool (below 25°C) and dry place
- Protected from light & moisture
- Keep out of the reach of children